Myxedema coma accompanied by sick sinus syndrome and hypoventilation: A case report

Ko Harada, Shuntaro Murakami, Kazuki Tokumasu, Yu Togawa, Fumio Otsuka

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Myxedema coma is an emergency presentation of hypothyroidism, and cardiopulmonary manifestations of the disease are related to a high mortality rate. We herein report a case of myxedema coma accompanied by sick sinus syndrome requiring temporary cardiac pacing and hypercapnic respiratory failure in an 87-year-old woman. This case is unique because both of the cardiac and pulmonary manifestations were reversible and successfully treated with thyroid hormone replacement. Our case indicates that early detection of the condition and administration of levothyroxine are essential to improve the life-threatening condition and avoid invasive treatment such as permanent pacemaker implantation or intubation.

Original languageEnglish
Pages (from-to)206-208
Number of pages3
JournalJournal of General and Family Medicine
Issue number5
Publication statusPublished - Sept 2019


  • hypercapnic respiratory failure
  • myxedema coma
  • sick sinus syndrome

ASJC Scopus subject areas

  • Family Practice
  • Geriatrics and Gerontology
  • Internal Medicine


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