Nanosized silver-anionic clay matrix as nanostructured ensembles with antimicrobial activity

Gabriela Carja, Yoshikazu Kameshima, Akira Nakajima, Cristian Dranca, Kiyoshi Okada

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)


Nanostructured ensembles of silver nanoparticles/zinc-substituted anionic clay matrix (Ag/ZnLDH) were obtained by a simple synthetic route in which reconstruction of the layered clay, synthesis of the silver nanoparticles and their organisation on the clay surface took place in a single step at room temperature. The morphology, composition and phase structure of the prepared powders were characterised by X-ray diffraction, infrared spectroscopy, transmission electron microscopy, X-ray photoelectron spectroscopy and N2 adsorption. Results showed that the silver-anionic clay nanoarchitecture consists of nanoparticles of silver (average size 7 nm) deposited on the larger nanoparticles of clay (average size 85 nm). The antimicrobial activity was examined by disk diffusion assay and minimal inhibitory concentration determination as a function of x, where x is a controlled variable parameter that represents the length of time since the sample was synthesised. Ag/ZnLDH showed more stable antimicrobial properties than the unsupported nanosized silver.

Original languageEnglish
Pages (from-to)534-539
Number of pages6
JournalInternational Journal of Antimicrobial Agents
Issue number6
Publication statusPublished - Dec 2009
Externally publishedYes


  • Antimicrobial properties
  • LDH anionic clay
  • Nanostructured ensembles
  • Silver nanoparticles

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)


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