Nasopharyngeal low-grade papillary schneiderian carcinoma with cervical metastasis

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1 Citation (Scopus)


Low-grade papillary Schneiderian carcinoma (LGPSC) is a rare and newly described type of cancer arising from the Schneiderian epithelium. Owing to cellular atypia, it is difficult to differentiate this type from other papillomas and malignancies. Although this condition remains unclear, it is associated with mortality and recurrence. Therefore, treating physicians should be aware of the possibility of LGPSC for prompt diagnosis and treatment. In this article, we present an additional case of nasopharyngeal LGPSC with cervical lymph node metastasis and reviewed the 14 cases reported thus far in the literature. A 76-year-old female was referred to our department for detailed examination of nasopharyngeal and cervical lymph node tumors detected by positron emission tomography-computed tomography. Based on the biopsy of the nasopharyngeal tumor, we suspected LGPSC. Considering the clinical course and pathological findings, the patient was diagnosed with cervical lymph node metastasis through neck dissection. We performed radiotherapy for the primary lesion of the nasopharynx, which led to the disappearance of the tumor. After 13 months following the radiotherapy, the patient died from a recurrence of retroperitoneal liposarcoma without the recurrence of LGPSC.

Original languageEnglish
JournalAuris Nasus Larynx
Publication statusAccepted/In press - 2023


  • Low-grade papillary Schneiderian carcinoma
  • Lymph node metastasis
  • Nasopharyngeal carcinoma
  • Schneiderian papilloma

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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