TY - JOUR
T1 - Nationwide epidemiological survey of idiopathic sudden sensorineural hearing loss in Japan
AU - Kitoh, Ryosuke
AU - Nishio, Shin Ya
AU - Ogawa, Kaoru
AU - Kanzaki, Sho
AU - Hato, Naohito
AU - Sone, Michihiko
AU - Fukuda, Satoshi
AU - Hara, Akira
AU - Ikezono, Tetsuo
AU - Ishikawa, Kotaro
AU - Iwasaki, Satoshi
AU - Kaga, Kimitaka
AU - Kakehata, Seiji
AU - Matsubara, Atsushi
AU - Matsunaga, Tatsuo
AU - Murata, Takaaki
AU - Naito, Yasushi
AU - Nakagawa, Takashi
AU - Nishizaki, Kazunori
AU - Noguchi, Yoshihiro
AU - Sano, Hajime
AU - Sato, Hiroaki
AU - Suzuki, Mikio
AU - Shojaku, Hideo
AU - Takahashi, Haruo
AU - Takeda, Hidehiko
AU - Tono, Testuya
AU - Yamashita, Hiroshi
AU - Yamasoba, Tatsuya
AU - Usami, Shin Ichi
N1 - Funding Information:
This study was supported by a Health and Labour Sciences Research Grant for Comprehensive Research on Disability Health and Welfare from the Ministry of Health, Labour and Welfare, Japan (http://www.mhlw.go.jp/english/) (S.U).
Publisher Copyright:
© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/3/10
Y1 - 2017/3/10
N2 - Objectives: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. Methods: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated. Statistical analysis was performed to clarify the factors associated with the severity of hearing impairment and prognosis. Results: There were significant correlations between the severity of hearing loss and diabetes mellitus, kidney disease, past history of brain infarction, heart disease, age (under 16 years/elderly), and symptoms of vertigo/dizziness. We also analyzed the prognostic factors for idiopathic SSNHL, and found that the severity of hearing loss (Grade 3 or 4), heart disease, aged 65 years or over, time from onset to treatment (over 7 days), and symptoms of vertigo/dizziness were all significantly related to poor prognosis. Conclusion: The present large-scale clinical survey revealed current epidemiological trends for idiopathic sudden sensorineural hearing loss (SSNHL) and various factors associated with the severity of hearing impairment and prognosis.
AB - Objectives: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. Methods: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated. Statistical analysis was performed to clarify the factors associated with the severity of hearing impairment and prognosis. Results: There were significant correlations between the severity of hearing loss and diabetes mellitus, kidney disease, past history of brain infarction, heart disease, age (under 16 years/elderly), and symptoms of vertigo/dizziness. We also analyzed the prognostic factors for idiopathic SSNHL, and found that the severity of hearing loss (Grade 3 or 4), heart disease, aged 65 years or over, time from onset to treatment (over 7 days), and symptoms of vertigo/dizziness were all significantly related to poor prognosis. Conclusion: The present large-scale clinical survey revealed current epidemiological trends for idiopathic sudden sensorineural hearing loss (SSNHL) and various factors associated with the severity of hearing impairment and prognosis.
KW - Idiopathic sudden sensorineural hearing loss
KW - corticosteroids
KW - epidemiological survey
KW - intratympanic
KW - prognostic factors
KW - severity of hearing impairment
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U2 - 10.1080/00016489.2017.1297537
DO - 10.1080/00016489.2017.1297537
M3 - Article
C2 - 28394652
AN - SCOPUS:85017282395
SN - 0001-6489
VL - 137
SP - S8-S16
JO - Acta Oto-Laryngologica
JF - Acta Oto-Laryngologica
ER -
