Nazarov cyclization of an indolyl vinyl ketone promoted by acetyl chloride and sodium iodide: Formal synthesis of Bruceolline e

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7 Citations (Scopus)

Abstract

An acetyl chloride/NaI-mediated Nazarov-type cyclization of an indolyl vinyl ketone was developed to give a cyclopenta[b]indole in high yield. An acyl Finkelstein reaction is a key feature for this unprecedented Nazarov-type cyclization.

Original languageEnglish
Pages (from-to)490-500
Number of pages11
JournalHeterocycles
Volume96
Issue number3
DOIs
Publication statusPublished - 2018
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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