Negishi alkyl-aryl cross-coupling catalyzed by Rh: Efficiency of novel tripodal 3-diphenylphosphino-2-(diphenylphosphino)methyl-2-methylpropyl acetate ligand

Syogo Ejiri; Shunsuke Odo; Hideki Takahashi; Yugo Nishimura; Kazuma Gotoh; Yasushi Nishihara; Kentaro Takagi

doi:10.1021/ol100210u

Negishi alkyl-aryl cross-coupling catalyzed by Rh: Efficiency of novel tripodal 3-diphenylphosphino-2-(diphenylphosphino)methyl-2-methylpropyl acetate ligand

Syogo Ejiri, Shunsuke Odo, Hideki Takahashi, Yugo Nishimura, Kazuma Gotoh, Yasushi Nishihara, Kentaro Takagi

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

3-Diphenylphosphino-2-(diphenylphoshino)methyl-2-methylpropyl acetate acted as an efficient ligand for a Rh catalyst, achieving cross-coupling between arylzinc compounds bearing electron-withdrawing groups and alkyl electrophiles. The beneficial effect of the tripodal ligand and such aryl nucleophiles was discussed with regard to the specificity of the Rh catalysis.

Original language	English
Pages (from-to)	1692-1695
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	8
DOIs	https://doi.org/10.1021/ol100210u
Publication status	Published - Apr 16 2010

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol100210u

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abstract = "3-Diphenylphosphino-2-(diphenylphoshino)methyl-2-methylpropyl acetate acted as an efficient ligand for a Rh catalyst, achieving cross-coupling between arylzinc compounds bearing electron-withdrawing groups and alkyl electrophiles. The beneficial effect of the tripodal ligand and such aryl nucleophiles was discussed with regard to the specificity of the Rh catalysis.",

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AU - Ejiri, Syogo

AU - Odo, Shunsuke

AU - Takahashi, Hideki

AU - Nishimura, Yugo

AU - Gotoh, Kazuma

AU - Nishihara, Yasushi

AU - Takagi, Kentaro

PY - 2010/4/16

Y1 - 2010/4/16

N2 - 3-Diphenylphosphino-2-(diphenylphoshino)methyl-2-methylpropyl acetate acted as an efficient ligand for a Rh catalyst, achieving cross-coupling between arylzinc compounds bearing electron-withdrawing groups and alkyl electrophiles. The beneficial effect of the tripodal ligand and such aryl nucleophiles was discussed with regard to the specificity of the Rh catalysis.

AB - 3-Diphenylphosphino-2-(diphenylphoshino)methyl-2-methylpropyl acetate acted as an efficient ligand for a Rh catalyst, achieving cross-coupling between arylzinc compounds bearing electron-withdrawing groups and alkyl electrophiles. The beneficial effect of the tripodal ligand and such aryl nucleophiles was discussed with regard to the specificity of the Rh catalysis.

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Negishi alkyl-aryl cross-coupling catalyzed by Rh: Efficiency of novel tripodal 3-diphenylphosphino-2-(diphenylphosphino)methyl-2-methylpropyl acetate ligand

Abstract

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