New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata

Kai Zhang; Yong Li; Zhi Yi Ni; Man Li Zhang; Yu Fang Wang; Qing Wen Shi; Chang Hong Huo; Françoise Sauriol; Hiromasa Kiyota; Yu Cheng Gu; Mei Dong

doi:10.1002/hlca.201200045

New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata

Kai Zhang, Yong Li, Zhi Yi Ni, Man Li Zhang, Yu Fang Wang, Qing Wen Shi, Chang Hong Huo, Françoise Sauriol, Hiromasa Kiyota, Yu Cheng Gu, Mei Dong

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2α,5α,7β, 9α,10β,12α)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1, 5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2α,5α,10β,14β)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.

Original language	English
Pages (from-to)	1566-1572
Number of pages	7
Journal	Helvetica Chimica Acta
Volume	95
Issue number	9
DOIs	https://doi.org/10.1002/hlca.201200045
Publication status	Published - Sept 2012
Externally published	Yes

Keywords

Taxanes
Taxus cuspidata

ASJC Scopus subject areas

Catalysis
Biochemistry
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1002/hlca.201200045

Cite this

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title = "New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata",

abstract = "Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2α,5α,7β, 9α,10β,12α)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1, 5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2α,5α,10β,14β)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.",

keywords = "Taxanes, Taxus cuspidata",

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year = "2012",

month = sep,

doi = "10.1002/hlca.201200045",

language = "English",

volume = "95",

pages = "1566--1572",

journal = "Helvetica Chimica Acta",

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T1 - New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata

AU - Zhang, Kai

AU - Li, Yong

AU - Ni, Zhi Yi

AU - Zhang, Man Li

AU - Wang, Yu Fang

AU - Shi, Qing Wen

AU - Huo, Chang Hong

AU - Sauriol, Françoise

AU - Kiyota, Hiromasa

AU - Gu, Yu Cheng

AU - Dong, Mei

PY - 2012/9

Y1 - 2012/9

N2 - Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2α,5α,7β, 9α,10β,12α)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1, 5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2α,5α,10β,14β)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.

AB - Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2α,5α,7β, 9α,10β,12α)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1, 5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2α,5α,10β,14β)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.

KW - Taxanes

KW - Taxus cuspidata

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JF - Helvetica Chimica Acta

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ER -

New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata

Abstract

Keywords

ASJC Scopus subject areas

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