TY - JOUR
T1 - New concept bioceramics composed of octacalcium phosphate (OCP) and dicarboxylic acid-intercalated OCP via hydrothermal hot-pressing
AU - Ishihara, Shiho
AU - Matsumoto, Takuya
AU - Onoki, Takamasa
AU - Sohmura, Taiji
AU - Nakahira, Atsushi
N1 - Funding Information:
This work was partially supported by a Grant-in-Aid from The Ministry of Education, Culture, Sports, Science and Technology, Japan.
PY - 2009/8/1
Y1 - 2009/8/1
N2 - Octacalcium phosphate (OCP) and adipic acid-intercalated complexed OCP (Adi-OCP) were synthesized. Moreover, we made ceramic bodies out of them through a hydrothermal hot-pressing (HHP) method. Characteristic features of both the powder and ceramics were investigated by the X-ray diffraction method (XRD). Surface morphology of the ceramics was observed by scanning electron microscopy (SEM). Density, compressive strength and pore size distribution of the ceramics were measured. Crystalline structure of the newly developed OCP ceramics had no phase transformation from the starting materials. Moreover, the newly developed OCP ceramics had good mechanical properties only through the HHP treatment with a temperature as low as 110 °C. In order to evaluate bioactivity, the ceramics were immersed in simulating body fluid (SBF). It was predicted that OCP and Adi-OCP had better bioactivity than that of conventional HAp ceramics.
AB - Octacalcium phosphate (OCP) and adipic acid-intercalated complexed OCP (Adi-OCP) were synthesized. Moreover, we made ceramic bodies out of them through a hydrothermal hot-pressing (HHP) method. Characteristic features of both the powder and ceramics were investigated by the X-ray diffraction method (XRD). Surface morphology of the ceramics was observed by scanning electron microscopy (SEM). Density, compressive strength and pore size distribution of the ceramics were measured. Crystalline structure of the newly developed OCP ceramics had no phase transformation from the starting materials. Moreover, the newly developed OCP ceramics had good mechanical properties only through the HHP treatment with a temperature as low as 110 °C. In order to evaluate bioactivity, the ceramics were immersed in simulating body fluid (SBF). It was predicted that OCP and Adi-OCP had better bioactivity than that of conventional HAp ceramics.
KW - Biomaterials
KW - Organic/inorganic hybrid
KW - Sustainable drug release
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U2 - 10.1016/j.msec.2009.02.023
DO - 10.1016/j.msec.2009.02.023
M3 - Article
AN - SCOPUS:67651102734
SN - 0928-4931
VL - 29
SP - 1885
EP - 1888
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
IS - 6
ER -