New hybrid nanostructures based on oxacillin-hydrotalcite-like anionic clays and their textural properties

Gabriela Carja; Yoshizaku Kameshima; Gabriela Ciobanu; Horia Chiriac; Kiyoshi Okada

doi:10.1016/j.micron.2007.12.001

New hybrid nanostructures based on oxacillin-hydrotalcite-like anionic clays and their textural properties

Gabriela Carja, Yoshizaku Kameshima, Gabriela Ciobanu, Horia Chiriac, Kiyoshi Okada

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

New hybrid nanostructures based on inorganic matrices of hydrotalcite-like anionic clays (HT) incorporated with oxacillin are obtained by using calcinations-restructure method. XRD and TEM analyses are used to study the structural and textural characteristics of the clay containing hybrids. When nanoparticles of iron oxides are loaded on the layered anionic clay matrix a more effective delivery system of the drug is obtained. The results can be used to reduce the toxic side effects of oxacillin (e.g. upset stomach, diarrhea, cholestastic hepatitis), its aggregation process in aqueous solutions and also can open new perspectives for targeted the drug delivery.

Original language	English
Pages (from-to)	147-150
Number of pages	4
Journal	Micron
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/j.micron.2007.12.001
Publication status	Published - Jan 2009
Externally published	Yes

Keywords

Drug delivery
Hydrotalcite
Layered double hydroxides
Oxacillin
TEM

ASJC Scopus subject areas

Structural Biology
Materials Science(all)
Physics and Astronomy(all)
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.micron.2007.12.001

Cite this

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title = "New hybrid nanostructures based on oxacillin-hydrotalcite-like anionic clays and their textural properties",

abstract = "New hybrid nanostructures based on inorganic matrices of hydrotalcite-like anionic clays (HT) incorporated with oxacillin are obtained by using calcinations-restructure method. XRD and TEM analyses are used to study the structural and textural characteristics of the clay containing hybrids. When nanoparticles of iron oxides are loaded on the layered anionic clay matrix a more effective delivery system of the drug is obtained. The results can be used to reduce the toxic side effects of oxacillin (e.g. upset stomach, diarrhea, cholestastic hepatitis), its aggregation process in aqueous solutions and also can open new perspectives for targeted the drug delivery.",

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AU - Carja, Gabriela

AU - Kameshima, Yoshizaku

AU - Ciobanu, Gabriela

AU - Chiriac, Horia

AU - Okada, Kiyoshi

PY - 2009/1

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AB - New hybrid nanostructures based on inorganic matrices of hydrotalcite-like anionic clays (HT) incorporated with oxacillin are obtained by using calcinations-restructure method. XRD and TEM analyses are used to study the structural and textural characteristics of the clay containing hybrids. When nanoparticles of iron oxides are loaded on the layered anionic clay matrix a more effective delivery system of the drug is obtained. The results can be used to reduce the toxic side effects of oxacillin (e.g. upset stomach, diarrhea, cholestastic hepatitis), its aggregation process in aqueous solutions and also can open new perspectives for targeted the drug delivery.

KW - Drug delivery

KW - Hydrotalcite

KW - Layered double hydroxides

KW - Oxacillin

KW - TEM

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New hybrid nanostructures based on oxacillin-hydrotalcite-like anionic clays and their textural properties

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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