New taxanes from the seeds of Taxus mairei

Q. W. Shi; Z. P. Li; C. L. Wang; M. L. Zhang; N. Choony; H. Kiyota

doi:10.1080/10286020500172848

New taxanes from the seeds of Taxus mairei

Q. W. Shi, Z. P. Li, C. L. Wang, M. L. Zhang, N. Choony, H. Kiyota

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Two new taxoid metabolites were isolated from the methanol extract of the Taxus mairei seeds. Their structures were established as 2α-hydroxy- 9α,10β,13α-triacetoxy-5α-cinnamoyloxytaxa-11-en-4β, 20-epoxide ( 1 ) and 2′-acetyl taxol ( 2 ) on the basis of spectral analysis.

Original language	English
Pages (from-to)	431-437
Number of pages	7
Journal	Journal of Asian Natural Products Research
Volume	8
Issue number	5
DOIs	https://doi.org/10.1080/10286020500172848
Publication status	Published - Jul 1 2006
Externally published	Yes

Keywords

2′-Acetyl taxol
Taxaceae
Taxanes
Taxol analogue
Taxus mairei
Yew

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1080/10286020500172848

Cite this

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title = "New taxanes from the seeds of Taxus mairei",

abstract = "Two new taxoid metabolites were isolated from the methanol extract of the Taxus mairei seeds. Their structures were established as 2α-hydroxy- 9α,10β,13α-triacetoxy-5α-cinnamoyloxytaxa-11-en-4β, 20-epoxide ( 1 ) and 2′-acetyl taxol ( 2 ) on the basis of spectral analysis.",

keywords = "2′-Acetyl taxol, Taxaceae, Taxanes, Taxol analogue, Taxus mairei, Yew",

author = "Shi, {Q. W.} and Li, {Z. P.} and Wang, {C. L.} and Zhang, {M. L.} and N. Choony and H. Kiyota",

note = "Funding Information: The work described in this paper was co-supported by the Foundation for Researching New Drugs of China (no. 2003AA2Z3527) and Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of People{\textquoteright}s Republic of China.",

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doi = "10.1080/10286020500172848",

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TY - JOUR

T1 - New taxanes from the seeds of Taxus mairei

AU - Shi, Q. W.

AU - Li, Z. P.

AU - Wang, C. L.

AU - Zhang, M. L.

AU - Choony, N.

AU - Kiyota, H.

N1 - Funding Information: The work described in this paper was co-supported by the Foundation for Researching New Drugs of China (no. 2003AA2Z3527) and Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of People’s Republic of China.

PY - 2006/7/1

Y1 - 2006/7/1

N2 - Two new taxoid metabolites were isolated from the methanol extract of the Taxus mairei seeds. Their structures were established as 2α-hydroxy- 9α,10β,13α-triacetoxy-5α-cinnamoyloxytaxa-11-en-4β, 20-epoxide ( 1 ) and 2′-acetyl taxol ( 2 ) on the basis of spectral analysis.

AB - Two new taxoid metabolites were isolated from the methanol extract of the Taxus mairei seeds. Their structures were established as 2α-hydroxy- 9α,10β,13α-triacetoxy-5α-cinnamoyloxytaxa-11-en-4β, 20-epoxide ( 1 ) and 2′-acetyl taxol ( 2 ) on the basis of spectral analysis.

KW - 2′-Acetyl taxol

KW - Taxaceae

KW - Taxanes

KW - Taxol analogue

KW - Taxus mairei

KW - Yew

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JF - Journal of Asian Natural Products Research

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New taxanes from the seeds of Taxus mairei

Abstract

Keywords

ASJC Scopus subject areas

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