TY - GEN
T1 - NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex
AU - Xu, Mingdi
AU - Takata, Hirotsugu
AU - Ge, Sheng
AU - Hayami, Takehito
AU - Yamasaki, Takao
AU - Tobimatsu, Shozo
AU - Iramina, Keiji
PY - 2007
Y1 - 2007
N2 - To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the Angers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).
AB - To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the Angers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).
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U2 - 10.1109/IEMBS.2007.4352834
DO - 10.1109/IEMBS.2007.4352834
M3 - Conference contribution
C2 - 18002500
AN - SCOPUS:57649142813
SN - 1424407885
SN - 9781424407880
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 2492
EP - 2495
BT - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
T2 - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Y2 - 23 August 2007 through 26 August 2007
ER -
