Nitric oxide metabolites and adrenomedullin in human breast milk

Naoko Ohta; Hirokazu Tsukahara; Yusei Ohshima; Manabu Nishii; Yasuyo Ogawa; Kyouichi Sekine; Kenkou Kasuga; Mitsufumi Mayumi

doi:10.1016/j.earlhumdev.2004.04.002

Nitric oxide metabolites and adrenomedullin in human breast milk

Naoko Ohta, Hirokazu Tsukahara, Yusei Ohshima, Manabu Nishii, Yasuyo Ogawa, Kyouichi Sekine, Kenkou Kasuga, Mitsufumi Mayumi

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.

Original language	English
Pages (from-to)	61-65
Number of pages	5
Journal	Early Human Development
Volume	78
Issue number	1
DOIs	https://doi.org/10.1016/j.earlhumdev.2004.04.002
Publication status	Published - Jun 2004
Externally published	Yes

Keywords

Adrenomedullin
Human milk
Nitric oxide

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.earlhumdev.2004.04.002

Cite this

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title = "Nitric oxide metabolites and adrenomedullin in human breast milk",

abstract = "We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.",

keywords = "Adrenomedullin, Human milk, Nitric oxide",

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note = "Funding Information: This work was supported by a grant (no. 14370244) from the Japanese Ministry of Education, Culture, Sports, Science and Technology.",

year = "2004",

month = jun,

doi = "10.1016/j.earlhumdev.2004.04.002",

language = "English",

volume = "78",

pages = "61--65",

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number = "1",

}

TY - JOUR

T1 - Nitric oxide metabolites and adrenomedullin in human breast milk

AU - Ohta, Naoko

AU - Tsukahara, Hirokazu

AU - Ohshima, Yusei

AU - Nishii, Manabu

AU - Ogawa, Yasuyo

AU - Sekine, Kyouichi

AU - Kasuga, Kenkou

AU - Mayumi, Mitsufumi

N1 - Funding Information: This work was supported by a grant (no. 14370244) from the Japanese Ministry of Education, Culture, Sports, Science and Technology.

PY - 2004/6

Y1 - 2004/6

N2 - We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.

AB - We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.

KW - Adrenomedullin

KW - Human milk

KW - Nitric oxide

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DO - 10.1016/j.earlhumdev.2004.04.002

M3 - Article

C2 - 15177673

AN - SCOPUS:2642559437

SN - 0378-3782

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EP - 65

JO - Screening

JF - Screening

IS - 1

ER -

Nitric oxide metabolites and adrenomedullin in human breast milk

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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