Nitric oxide metabolites and adrenomedullin in human breast milk

Naoko Ohta, Hirokazu Tsukahara, Yusei Ohshima, Manabu Nishii, Yasuyo Ogawa, Kyouichi Sekine, Kenkou Kasuga, Mitsufumi Mayumi

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalEarly Human Development
Issue number1
Publication statusPublished - Jun 2004
Externally publishedYes


  • Adrenomedullin
  • Human milk
  • Nitric oxide

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology


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