Noninvasive cross-sectional imaging of proximal caries using swept-source optical coherence tomography (SS-OCT) in vivo

Yasushi Shimada, Hisaichi Nakagawa, Alireza Sadr, Ikumi Wada, Masatoshi Nakajima, Toru Nikaido, Masayuki Otsuki, Junji Tagami, Yasunori Sumi

Research output: Contribution to journalArticlepeer-review

73 Citations (Scopus)


The aim of this study was to determine the diagnostic accuracy of swept-source optical coherent tomography (SS-OCT) in detecting and estimating the depth of proximal caries in posterior teeth in vivo. SS-OCT images and bitewing radiographs were obtained from 86 proximal surfaces of 53 patients. Six examiners scored the locations according to a caries lesion depth scale (0-4) using SS-OCT and the radiographs. The results were compared with clinical observations obtained after the treatment. SS-OCT could detect the presence of proximal caries in tomograms that were synthesized based on the backscatter signal obtained from the proximal carious lesion through occlusal enamel. SS-OCT showed significantly higher sensitivity and larger area under the receiver operating characteristic curve than radiographs for the detection of cavitated enamel lesions and dentin caries (Student's t -test, p < 0.05). SS-OCT appears to be a more reliable and accurate method than bitewing radiographs for the detection and estimation of the depth of proximal lesions in the clinical environment.

Original languageEnglish
Pages (from-to)506-513
Number of pages8
JournalJournal of Biophotonics
Issue number7
Publication statusPublished - Jul 2014
Externally publishedYes


  • Bitewing radiograph
  • Proximal caries
  • ROC analysis
  • SS-OCT
  • Sensitivity
  • Specificity
  • in vivo

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Physics and Astronomy(all)


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