TY - JOUR
T1 - Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis
T2 - a case investigation
AU - Hagiya, Hideharu
AU - Aoki, Kotaro
AU - Akeda, Yukihiro
AU - Sakamoto, Noriko
AU - Yamamoto, Norihisa
AU - Yoshida, Hisao
AU - Nishi, Isao
AU - Ishii, Yoshikazu
AU - Tomono, Kazunori
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.
AB - Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.
KW - Autopsy
KW - Carbapenem-resistant Enterobacteriaceae
KW - Nosocomial infection
KW - Pathological dissection room
KW - Whole-genome sequencing
UR - http://www.scopus.com/inward/record.url?scp=85010934343&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85010934343&partnerID=8YFLogxK
U2 - 10.1007/s15010-017-0986-3
DO - 10.1007/s15010-017-0986-3
M3 - Article
C2 - 28138943
AN - SCOPUS:85010934343
SN - 0300-8126
VL - 45
SP - 221
EP - 225
JO - Infection
JF - Infection
IS - 2
ER -
