Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis: a case investigation

Hideharu Hagiya; Kotaro Aoki; Yukihiro Akeda; Noriko Sakamoto; Norihisa Yamamoto; Hisao Yoshida; Isao Nishi; Yoshikazu Ishii; Kazunori Tomono

doi:10.1007/s15010-017-0986-3

Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis: a case investigation

Hideharu Hagiya
, Kotaro Aoki
, Yukihiro Akeda
, Noriko Sakamoto
, Norihisa Yamamoto
, Hisao Yoshida
, Isao Nishi
, Yoshikazu Ishii
, Kazunori Tomono

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.

Original language	English
Pages (from-to)	221-225
Number of pages	5
Journal	Infection
Volume	45
Issue number	2
DOIs	https://doi.org/10.1007/s15010-017-0986-3
Publication status	Published - Apr 1 2017
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Autopsy
Carbapenem-resistant Enterobacteriaceae
Nosocomial infection
Pathological dissection room
Whole-genome sequencing

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1007/s15010-017-0986-3

Cite this

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title = "Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis: a case investigation",

abstract = "Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.",

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doi = "10.1007/s15010-017-0986-3",

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T1 - Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis

T2 - a case investigation

AU - Hagiya, Hideharu

AU - Aoki, Kotaro

AU - Akeda, Yukihiro

AU - Sakamoto, Noriko

AU - Yamamoto, Norihisa

AU - Yoshida, Hisao

AU - Nishi, Isao

AU - Ishii, Yoshikazu

AU - Tomono, Kazunori

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.

AB - Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.

KW - Autopsy

KW - Carbapenem-resistant Enterobacteriaceae

KW - Nosocomial infection

KW - Pathological dissection room

KW - Whole-genome sequencing

UR - https://www.scopus.com/pages/publications/85010934343

UR - https://www.scopus.com/pages/publications/85010934343#tab=citedBy

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AN - SCOPUS:85010934343

SN - 0300-8126

VL - 45

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EP - 225

JO - Infection

JF - Infection

IS - 2

ER -

Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis: a case investigation

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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