Novel synthesis of benzoxazoles from o-nitrophenols and amines

Hiromi Nishioka; Yukiko Ohmori; Yumiko Iba; Eri Tsuda; Takashi Harayama

doi:10.3987/COM-04-S(P)11

Novel synthesis of benzoxazoles from o-nitrophenols and amines

Hiromi Nishioka, Yukiko Ohmori, Yumiko Iba, Eri Tsuda, Takashi Harayama

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO₂Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.

Original language	English
Pages (from-to)	193-198
Number of pages	6
Journal	Heterocycles
Volume	64
DOIs	https://doi.org/10.3987/COM-04-S(P)11
Publication status	Published - Dec 31 2004

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

Access to Document

10.3987/COM-04-S(P)11

Cite this

@article{8e6ee94077384b398e883761cf5e7ffb,

title = "Novel synthesis of benzoxazoles from o-nitrophenols and amines",

abstract = "o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO2Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.",

author = "Hiromi Nishioka and Yukiko Ohmori and Yumiko Iba and Eri Tsuda and Takashi Harayama",

year = "2004",

month = dec,

day = "31",

doi = "10.3987/COM-04-S(P)11",

language = "English",

volume = "64",

pages = "193--198",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

}

TY - JOUR

T1 - Novel synthesis of benzoxazoles from o-nitrophenols and amines

AU - Nishioka, Hiromi

AU - Ohmori, Yukiko

AU - Iba, Yumiko

AU - Tsuda, Eri

AU - Harayama, Takashi

PY - 2004/12/31

Y1 - 2004/12/31

N2 - o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO2Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.

AB - o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO2Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.

UR - http://www.scopus.com/inward/record.url?scp=33646896972&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646896972&partnerID=8YFLogxK

U2 - 10.3987/COM-04-S(P)11

DO - 10.3987/COM-04-S(P)11

M3 - Article

AN - SCOPUS:33646896972

SN - 0385-5414

VL - 64

SP - 193

EP - 198

JO - Heterocycles

JF - Heterocycles

ER -

Novel synthesis of benzoxazoles from o-nitrophenols and amines

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this