One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione

Yasuo Takeuchi; Keiko Sakagawa; Masumi Kubo; Masatoshi Yamato

doi:10.1248/cpb.34.1323

One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione

Yasuo Takeuchi, Keiko Sakagawa, Masumi Kubo, Masatoshi Yamato

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis of sulfides from alcohols and benzoxazoline-2-thione (I) was studied to establish its generality and the mechanism of the reaction. A one-flask synthesis of sulfides from alcohols was developed. According to this procedure, various sulfides were prepared without the use of ill-smelling thiols. Moreover, partial sulfenylation of diols to give sulfenyl alcohols was achieved.

Original language	English
Pages (from-to)	1323-1327
Number of pages	5
Journal	Chemical and Pharmaceutical Bulletin
Volume	34
Issue number	3
DOIs	https://doi.org/10.1248/cpb.34.1323
Publication status	Published - 1986

Keywords

benzoxazoline-2-thione
one-flask synthesis
partial sulfenylation
sulfenyl alcohol
sulfide

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.34.1323

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AU - Yamato, Masatoshi

PY - 1986

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AB - The synthesis of sulfides from alcohols and benzoxazoline-2-thione (I) was studied to establish its generality and the mechanism of the reaction. A one-flask synthesis of sulfides from alcohols was developed. According to this procedure, various sulfides were prepared without the use of ill-smelling thiols. Moreover, partial sulfenylation of diols to give sulfenyl alcohols was achieved.

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KW - one-flask synthesis

KW - partial sulfenylation

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One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione

Abstract

Keywords

ASJC Scopus subject areas

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