A one-pot approach to 3,3′-bisindolylmethane derivatives from nitrobenzene derivatives through the Bartoli indole synthesis was developed, in which the acid used to quench the reaction markedly affected its outcome. Quenching the reaction with concd HCl produced 3,3′-bisindolylmethane in contrast to the formation of 7-substituted indole by quenching with NH 4Cl.
|Number of pages||4|
|Publication status||Published - Jul 19 2013|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry