One-pot substitution-rearrangement reaction of 2-chloroglycidic ester: Effective protocol for the preparation of 3-arylsulfenyl-2-keto ester

Takuzo Komiyama, Yutaka Takaguchi, Sadao Tsuboi

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The one-pot substitution-rearrangement reaction of 2-chloroglycidic ester is reported. Treatment of 2-chloroglycidic ester with sodium arylthiolate at room temperature results in the formation of 3-arylsulfenyl-2-keto ester in excellent to good yields.

    Original languageEnglish
    Pages (from-to)265-269
    Number of pages5
    JournalSynthetic Communications
    Volume36
    Issue number3
    DOIs
    Publication statusPublished - Jan 1 2006

    Keywords

    • 2-Chloroglycidic ester
    • Darzens condensation
    • Dichloroacetate
    • Substitution-rearrangement reaction

    ASJC Scopus subject areas

    • Organic Chemistry

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