Optic neuritis associated with myelodysplastic syndrome accompanied by eosinophilic crisis

Joji Nagasaki, Mitsutaka Nishimoto, Hirohisa Nakamae, Takahiko Nakane, Hideo Koh, Kumiko Yoshimoto, Kunihiko Shiraki, Masayuki Hino

Research output: Contribution to journalArticlepeer-review


Myelodysplastic syndrome (MDS) was diagnosed in a 64-year-old man. Three months later, he presented with right-sided visual loss. A diagnosis of optic neuritis caused by both ischemic and non-ischemic changes was established. Concurrently, prominent eosinophilia was seen in both the peripheral blood and bone marrow. A partial improvement of visual loss was obtained concomitant with a rapid decrease of the eosinophils after treatment with corticosteroids. Optic neuritis related to MDS is a rare condition and its etiology has not yet been identified. We herein report a case of optic neuritis associated with MDS and accompanied by an eosinophilic crisis.

Original languageEnglish
Pages (from-to)2241-2244
Number of pages4
JournalInternal Medicine
Issue number17
Publication statusPublished - Sept 1 2015
Externally publishedYes


  • Eosinophilic crisis
  • Myelodysplastic syndrome
  • Optic neuritis

ASJC Scopus subject areas

  • Internal Medicine


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