Outcome of trabeculectomy with prior intravitreal bevacizumab injection for neovascular glaucoma

Tetsuhiro Kawata, Naoko Yamamoto, Kyoko Matsushita, Tomoko Naito, Hiroshi Ohtsuki, Makiko Takahashi

Research output: Contribution to journalArticlepeer-review


Purpose : To compare the outcome of trabeculectomy for neovascular glaucoma with or without prior in- travitreal injection of bevacizumab. Cases and Method : We reviewed 26 eyes of 24 cases who received trabeculectomy during the past 39 months. Neovascular glaucoma was due to diabetic retinopathy 17 eyes, retinal vein occlusion 6 eyes, and others 3 eyes. Nine eyes received intravitreal bevacizumab one to 14 days before surgery. Results : Final intraocular pressure (IOP) averaged 11.0± 1.4 mmHg in 9 eyes receiving bevacizumb and 9.0± 1.4 mmHg in the other 17 eyes. When final IOP over 15 mmHg or additional treatment glaucoma was defined as death, rate of survival was 77.7% in 9 eyes receiving bevacizumab and 60.0% in the other 17 eyes 12 months after surgery. There was no significant difference between the two groups. Conclusion : Intravitreal injection of bevacizumab may decrease late complications of trabeculectomy and may induce early IOP control.

Original languageEnglish
Pages (from-to)1457-1460
Number of pages4
JournalJapanese Journal of Clinical Ophthalmology
Issue number9
Publication statusPublished - Sept 2009

ASJC Scopus subject areas

  • Ophthalmology


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