Regio- and stereoselective addition of a silyl-substituted alkynyl sulfide to various terminal alkynes proceeds in the presence of a palladium catalyst to give (Z)-1-thio-1,3-enynes, which are useful building blocks for the synthesis of polysubstituted 1,3-enynes. Addition to internal alkynes also takes place under solvent-free conditions (see scheme).
|Number of pages||5|
|Journal||Chemistry - An Asian Journal|
|Publication status||Published - Dec 2 2011|
- alkynyl sulfide
ASJC Scopus subject areas
- Organic Chemistry