Platisidines A-C, N-methylpyridinium alkaloids from an okinawan marine sponge of Plakortis species

Takaaki Kubota; Yuichiro Ishiguro; Sunao Yamamoto; Jane Fromont; Jun'Ichi Kobayashi

doi:10.3987/COM-09-S(S)131

Platisidines A-C, N-methylpyridinium alkaloids from an okinawan marine sponge of Plakortis species

Takaaki Kubota, Yuichiro Ishiguro, Sunao Yamamoto, Jane Fromont, Jun'Ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Three new N-methyl pyridinium alkaloids, platisidines A-C (13), were isolated from an Okinawan marine sponge of the genus Plakortis, and the structures were elucidated from spectroscopic data. The structures of platisidines A-C (13) were elucidated to be N-methyl nicotinic acid derivatives with a n-hexadecanoyl chain. Platisidines A-C (13) showed inhibitory activity against acetylcholinesterase.

Original language	English
Pages (from-to)	1407-1412
Number of pages	6
Journal	Heterocycles
Volume	80
Issue number	2
DOIs	https://doi.org/10.3987/COM-09-S(S)131
Publication status	Published - Mar 1 2010
Externally published	Yes

Keywords

Acetylcholinesterase Inhibitor
Plakortis species
Platisidines A-C
Pyridinium Alkaloid
Sponge

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3987/COM-09-S(S)131

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abstract = "Three new N-methyl pyridinium alkaloids, platisidines A-C (13), were isolated from an Okinawan marine sponge of the genus Plakortis, and the structures were elucidated from spectroscopic data. The structures of platisidines A-C (13) were elucidated to be N-methyl nicotinic acid derivatives with a n-hexadecanoyl chain. Platisidines A-C (13) showed inhibitory activity against acetylcholinesterase.",

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author = "Takaaki Kubota and Yuichiro Ishiguro and Sunao Yamamoto and Jane Fromont and Jun'Ichi Kobayashi",

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doi = "10.3987/COM-09-S(S)131",

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T1 - Platisidines A-C, N-methylpyridinium alkaloids from an okinawan marine sponge of Plakortis species

AU - Kubota, Takaaki

AU - Ishiguro, Yuichiro

AU - Yamamoto, Sunao

AU - Fromont, Jane

AU - Kobayashi, Jun'Ichi

PY - 2010/3/1

Y1 - 2010/3/1

N2 - Three new N-methyl pyridinium alkaloids, platisidines A-C (13), were isolated from an Okinawan marine sponge of the genus Plakortis, and the structures were elucidated from spectroscopic data. The structures of platisidines A-C (13) were elucidated to be N-methyl nicotinic acid derivatives with a n-hexadecanoyl chain. Platisidines A-C (13) showed inhibitory activity against acetylcholinesterase.

AB - Three new N-methyl pyridinium alkaloids, platisidines A-C (13), were isolated from an Okinawan marine sponge of the genus Plakortis, and the structures were elucidated from spectroscopic data. The structures of platisidines A-C (13) were elucidated to be N-methyl nicotinic acid derivatives with a n-hexadecanoyl chain. Platisidines A-C (13) showed inhibitory activity against acetylcholinesterase.

KW - Acetylcholinesterase Inhibitor

KW - Plakortis species

KW - Platisidines A-C

KW - Pyridinium Alkaloid

KW - Sponge

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SP - 1407

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Platisidines A-C, N-methylpyridinium alkaloids from an okinawan marine sponge of Plakortis species

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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