TY - JOUR
T1 - Pneumatical-Mechanical Tactile Stimulation Device for Somatotopic Mapping of Body Surface During fMRI
AU - Jia, Shikui
AU - Wang, Luyao
AU - Wang, Heng
AU - Lv, Xiaoyu
AU - Wu, Jinglong
AU - Yan, Tianyi
AU - Li, Chunlin
AU - Hu, Baomin
N1 - Funding Information:
Contract grant sponsor: National Natural Science Foundation of China; Contract grant numbers: 81671776, 61727807; Contract grant sponsor: Beijing Municipal Science and Technology Commission; Contract grant number: Z161100002616020; Contract grant sponsor: JSPS KAKENHI; Contract grant numbers: 18K18835, 18H01411, and 19KK0099.
Publisher Copyright:
© 2020 International Society for Magnetic Resonance in Medicine
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Background: There is a need for devices that allow reproducible stimulation of skin areas of humans for investigating somatosensory mapping of the whole-body surface. However, their design is not simple, due to the magnetic field of MRI scanners. Purpose: To accurately characterize the mapping of somatosensory presentation of the whole-body surface of subjects during functional (f)MRI scans. Study Type: Prospective. Population: A water phantom and six healthy participants (age 23–27 years; two males) were recruited for the fMRI experiment. Field Strength/Sequence: T1-weighted magnetization-prepared rapid acquisition gradient-echo, T2*-weighted gradient echo sequence at 3T. Assessment: The stimulation device for somatotopic mapping was composed of three units: an air-generating unit, a control unit, and an execution unit. The fMRI in response to tactile stimulation was measured to characterize somatotopic mapping of the right-side body consisting of hand, arm, and leg in six healthy subjects. Statistical Tests: Pared-samples t-test for the conditions in SII. Results: The pneumatical-mechanical tactile stimulation offered a wide range of stimulation intensities (0–400 g) in each channel. The predetermined physical pressure was successfully reached within ~5 msec and returned to baseline within 5 msec after the end of stimulation. With this tactile device, the digressive rate of the signal-to-noise ratio (SNR) (271.44 without the device, 269.68 with the device) was 0.65% in the magnetic field environment. For the fMRI experiment, the primary somatosensory activation contralateral to the stimulation site was detected in response to spatial task and attentive task. Data Conclusion: This stimulation device characterized the mapping of somatosensory representation of the whole-body surface in individual participants during fMRI scans. Level of Evidence: 2. Technical Efficacy Stage: 1. J. Magn. Reson. Imaging 2020;52:1093–1101.
AB - Background: There is a need for devices that allow reproducible stimulation of skin areas of humans for investigating somatosensory mapping of the whole-body surface. However, their design is not simple, due to the magnetic field of MRI scanners. Purpose: To accurately characterize the mapping of somatosensory presentation of the whole-body surface of subjects during functional (f)MRI scans. Study Type: Prospective. Population: A water phantom and six healthy participants (age 23–27 years; two males) were recruited for the fMRI experiment. Field Strength/Sequence: T1-weighted magnetization-prepared rapid acquisition gradient-echo, T2*-weighted gradient echo sequence at 3T. Assessment: The stimulation device for somatotopic mapping was composed of three units: an air-generating unit, a control unit, and an execution unit. The fMRI in response to tactile stimulation was measured to characterize somatotopic mapping of the right-side body consisting of hand, arm, and leg in six healthy subjects. Statistical Tests: Pared-samples t-test for the conditions in SII. Results: The pneumatical-mechanical tactile stimulation offered a wide range of stimulation intensities (0–400 g) in each channel. The predetermined physical pressure was successfully reached within ~5 msec and returned to baseline within 5 msec after the end of stimulation. With this tactile device, the digressive rate of the signal-to-noise ratio (SNR) (271.44 without the device, 269.68 with the device) was 0.65% in the magnetic field environment. For the fMRI experiment, the primary somatosensory activation contralateral to the stimulation site was detected in response to spatial task and attentive task. Data Conclusion: This stimulation device characterized the mapping of somatosensory representation of the whole-body surface in individual participants during fMRI scans. Level of Evidence: 2. Technical Efficacy Stage: 1. J. Magn. Reson. Imaging 2020;52:1093–1101.
KW - device
KW - fMRI
KW - pneumatical-mechanical
KW - somatosensory mapping
KW - tactile stimulation
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U2 - 10.1002/jmri.27144
DO - 10.1002/jmri.27144
M3 - Article
C2 - 32359119
AN - SCOPUS:85084224828
SN - 1053-1807
VL - 52
SP - 1093
EP - 1101
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 4
ER -