Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds

Kenji Sasaki; Tomohiro Funabashi; Hiromi Ohtomo; Taiji Nakayama; Takashi Hirota

Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds

Kenji Sasaki, Tomohiro Funabashi, Hiromi Ohtomo, Taiji Nakayama, Takashi Hirota

Research output: Contribution to journal › Article › peer-review

Abstract

Synthesis and separation of cis- and trans-1,2,4,5,5a,6,7,8,9,9a-decahydrobenz[h]imidazo[1,2-c]quinazolines and its precursors are described. Inhibitory activity against collagen-induced platelet aggregation for rabbit blood of these compounds and their benzologues at A ring is also evaluated.

Original language	English
Pages (from-to)	2251-2262
Number of pages	12
Journal	Heterocycles
Volume	41
Issue number	10
Publication status	Published - Oct 1 1995

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

Cite this

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AU - Ohtomo, Hiromi

AU - Nakayama, Taiji

AU - Hirota, Takashi

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AB - Synthesis and separation of cis- and trans-1,2,4,5,5a,6,7,8,9,9a-decahydrobenz[h]imidazo[1,2-c]quinazolines and its precursors are described. Inhibitory activity against collagen-induced platelet aggregation for rabbit blood of these compounds and their benzologues at A ring is also evaluated.

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Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds

Abstract

ASJC Scopus subject areas

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