Polycythemia vera diagnosed after esophageal variceal rupture

Yoshiyasu Kono; Akinobu Takaki; Hideo Gobara; Ken Ichi Matsuoka; Masato Nishino; Hiroyuki Okada; Kazuhide Yamamoto

doi:10.2169/internalmedicine.54.4687

Polycythemia vera diagnosed after esophageal variceal rupture

Yoshiyasu Kono, Akinobu Takaki, Hideo Gobara, Ken Ichi Matsuoka, Masato Nishino, Hiroyuki Okada, Kazuhide Yamamoto

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

Original language	English
Pages (from-to)	2395-2399
Number of pages	5
Journal	Internal Medicine
Volume	54
Issue number	18
DOIs	https://doi.org/10.2169/internalmedicine.54.4687
Publication status	Published - Sept 15 2015

Keywords

Esophagogastric varices
Polycythemia vera (PV)
Portal hypertension
Thrombosis

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.54.4687

Cite this

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title = "Polycythemia vera diagnosed after esophageal variceal rupture",

abstract = "Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.",

keywords = "Esophagogastric varices, Polycythemia vera (PV), Portal hypertension, Thrombosis",

author = "Yoshiyasu Kono and Akinobu Takaki and Hideo Gobara and Matsuoka, {Ken Ichi} and Masato Nishino and Hiroyuki Okada and Kazuhide Yamamoto",

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doi = "10.2169/internalmedicine.54.4687",

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T1 - Polycythemia vera diagnosed after esophageal variceal rupture

AU - Kono, Yoshiyasu

AU - Takaki, Akinobu

AU - Gobara, Hideo

AU - Matsuoka, Ken Ichi

AU - Nishino, Masato

AU - Okada, Hiroyuki

AU - Yamamoto, Kazuhide

PY - 2015/9/15

Y1 - 2015/9/15

N2 - Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

AB - Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

KW - Esophagogastric varices

KW - Polycythemia vera (PV)

KW - Portal hypertension

KW - Thrombosis

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Polycythemia vera diagnosed after esophageal variceal rupture

Abstract

Keywords

ASJC Scopus subject areas

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