Possibility of odontoblasts activity up-regulation due to orthodontic mechanical stress in mice

Keisuke Nakano; Rina Muraoka; Mihoko Tomida; Sachiko Matsuura; Norimasa Okafuji; Chong Huat Siar; Toshiyuki Kawakami

doi:10.2485/jhtb.19.13

Possibility of odontoblasts activity up-regulation due to orthodontic mechanical stress in mice

Keisuke Nakano, Rina Muraoka, Mihoko Tomida, Sachiko Matsuura, Norimasa Okafuji, Chong Huat Siar, Toshiyuki Kawakami

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Abstract: Using Waldo's method in mice, we examined the immunohistochemical expression of Runx2 and alkaline phosphatase (ALP) appearing in dental pulp cells, especially in odontoblasts, just after receiving experimental orthodontic mechanical stress, using Waldo's method in mice. The examination results demonstrated that some dental root pulp cells, especially some odontoblasts, expressed the Runx2 and ALP in a comparatively short time after receiving the stress. The results suggest that the stress may cause odontoblast activity up- regulation.

Original language	English
Pages (from-to)	13-16
Number of pages	4
Journal	Journal of Hard Tissue Biology
Volume	19
Issue number	1
DOIs	https://doi.org/10.2485/jhtb.19.13
Publication status	Published - 2010
Externally published	Yes

Keywords

Alkaline phosphatase (alp)
Dental pulp cells
Mechanical stress
Odontoblasts
Orthodontics
Runx2
Up-regulation

ASJC Scopus subject areas

Medicine (miscellaneous)
Biochemistry
Biomaterials
Orthopedics and Sports Medicine
Dentistry(all)
Cell Biology

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10.2485/jhtb.19.13

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title = "Possibility of odontoblasts activity up-regulation due to orthodontic mechanical stress in mice",

abstract = "Abstract: Using Waldo's method in mice, we examined the immunohistochemical expression of Runx2 and alkaline phosphatase (ALP) appearing in dental pulp cells, especially in odontoblasts, just after receiving experimental orthodontic mechanical stress, using Waldo's method in mice. The examination results demonstrated that some dental root pulp cells, especially some odontoblasts, expressed the Runx2 and ALP in a comparatively short time after receiving the stress. The results suggest that the stress may cause odontoblast activity up- regulation.",

keywords = "Alkaline phosphatase (alp), Dental pulp cells, Mechanical stress, Odontoblasts, Orthodontics, Runx2, Up-regulation",

author = "Keisuke Nakano and Rina Muraoka and Mihoko Tomida and Sachiko Matsuura and Norimasa Okafuji and Siar, {Chong Huat} and Toshiyuki Kawakami",

year = "2010",

doi = "10.2485/jhtb.19.13",

language = "English",

volume = "19",

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T1 - Possibility of odontoblasts activity up-regulation due to orthodontic mechanical stress in mice

AU - Nakano, Keisuke

AU - Muraoka, Rina

AU - Tomida, Mihoko

AU - Matsuura, Sachiko

AU - Okafuji, Norimasa

AU - Siar, Chong Huat

AU - Kawakami, Toshiyuki

PY - 2010

Y1 - 2010

N2 - Abstract: Using Waldo's method in mice, we examined the immunohistochemical expression of Runx2 and alkaline phosphatase (ALP) appearing in dental pulp cells, especially in odontoblasts, just after receiving experimental orthodontic mechanical stress, using Waldo's method in mice. The examination results demonstrated that some dental root pulp cells, especially some odontoblasts, expressed the Runx2 and ALP in a comparatively short time after receiving the stress. The results suggest that the stress may cause odontoblast activity up- regulation.

AB - Abstract: Using Waldo's method in mice, we examined the immunohistochemical expression of Runx2 and alkaline phosphatase (ALP) appearing in dental pulp cells, especially in odontoblasts, just after receiving experimental orthodontic mechanical stress, using Waldo's method in mice. The examination results demonstrated that some dental root pulp cells, especially some odontoblasts, expressed the Runx2 and ALP in a comparatively short time after receiving the stress. The results suggest that the stress may cause odontoblast activity up- regulation.

KW - Alkaline phosphatase (alp)

KW - Dental pulp cells

KW - Mechanical stress

KW - Odontoblasts

KW - Orthodontics

KW - Runx2

KW - Up-regulation

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DO - 10.2485/jhtb.19.13

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JO - Journal of Hard Tissue Biology

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Possibility of odontoblasts activity up-regulation due to orthodontic mechanical stress in mice

Abstract

Keywords

ASJC Scopus subject areas

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