Prenatal diagnosis of interrupted aortic arch: Usefulness of three-vessel and four-chamber views

Y. Hirano, H. Masuyama, K. Hayata, E. Eto, E. Nobumoto, Y. Hiramatsu

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Interrupted aortic arch (IAA) is fatal if not diagnosed. Prenatal diagnosis is helpful, but it is difficult to detect IAA and even more so to differentiate types A and B prenatally. Our objectives were to find a way to detect IAA using 2 views-three-vessel view (3VV) and four-chamber view (4CV)-and to differentiate between types A and B. We retrospectively analyzed fetal echocardiographic images and medical records of eight IAA patients. All eight patients had a ventricular septal defect (VSD) on 4CV. The aorta/main pulmonary artery (Ao/MPA) diameter ratio on 3VV was significantly low, which is characteristic of type B IAA. The left/right ventricular diameter (LV/RV) ratio on 4CV was 0.61± 0.17 for type A and almost 1.0 for type B. The thymus was not observed on 3VV in some type B IAA patients. These findings suggest that we could increase the number of prenatal diagnoses of IAA using the Ao/MPA ratio on 3VV and the presence of VSD on 4CV. Additionally, we could differentiate types A and B with the LV/RV ratio on 4CV, the Ao/MPA ratio, and the presence of a thymus on 3VV, which results in better management of IAA after birth.

Original languageEnglish
Pages (from-to)485-491
Number of pages7
JournalActa medica Okayama
Issue number6
Publication statusPublished - 2016


  • Aortic diameter/main pulmonary artery diameter ratio
  • Four-chamber view
  • Interrupted aortic arch
  • Three-vessel view
  • Ventricular septal defect

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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