Preparation of Nanocapsules with Alginate/Polylysine Complex Wall

Masahiko Abe, Kensuke Tanaka, Ai Nakayama, Tamotsu Kondo, Koji Tsuchiya, Veerapat Tantayakom, Takahiro Ohkubo, Hideki Sakai

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


This paper deals with a novel preparation method of nanocapsules with alginate/polylysine complex wall. The preparation method consisted of the following steps: dispersion of an aqueous sodium alginate solution into cyclohexane to give a W/O emulsion, preparation of calcium alginate gel beads by adding the emulsion into a calcium aerosol OT solution in cyclohexane, and alginate/polylysine complex wall formation on the surface of calcium alginate beads by adding the beads into an aqueous poly-L-lysine solution. The size of alginate/polylysine complex capsules thus prepared was found to be 100-500 nm. Moreover, an attempt was made to prepare much smaller capsules using a laboratory-made apparatus for electrocapillary emulsification and the capsule size could be reduced to about 40 nm.

Original languageEnglish
Pages (from-to)615-621
Number of pages7
JournalJournal of Oleo Science
Issue number12
Publication statusPublished - 2006
Externally publishedYes


  • alginate
  • electrocapillary emulsification
  • nanocapsule
  • polylysine

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)


Dive into the research topics of 'Preparation of Nanocapsules with Alginate/Polylysine Complex Wall'. Together they form a unique fingerprint.

Cite this