Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase

Satoshi Tanaka; Tetsuya Fukui; Jun Yamamoto; Yoh ichiro Shima; Toshiaki Kume; Makoto Ohgo; Atsushi Ichikawa

doi:10.1016/0167-4838(95)00185-W

Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase

Satoshi Tanaka, Tetsuya Fukui, Jun Yamamoto, Yoh ichiro Shima, Toshiaki Kume, Makoto Ohgo, Atsushi Ichikawa

Graduate School of Medicine Dentistry and Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Mature 53 kDa histidine decarboxylase (HDC) peptide is produced from a precursor 74 kDa peptide. The mechanism of specific cleavage by processing enzyme is unknown. Using the recombinant mouse 74 kDa HDC, we found that porcine pancreatic elastase specifically converted the inactive 74 kDa HDC to its active form of 53 kDa HDC.

Original language	English
Pages (from-to)	9-12
Number of pages	4
Journal	Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
Volume	1253
Issue number	1
DOIs	https://doi.org/10.1016/0167-4838(95)00185-W
Publication status	Published - Nov 15 1995

Keywords

(Mouse)
(Porcine)
Histidine decarboxylase
Mastocytoma
Pancreatic elastase
Sf9 cell

ASJC Scopus subject areas

Structural Biology
Biophysics
Biochemistry
Molecular Biology

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10.1016/0167-4838(95)00185-W

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Tanaka, S., Fukui, T., Yamamoto, J., Shima, Y. I., Kume, T., Ohgo, M., & Ichikawa, A. (1995). Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase. Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, 1253(1), 9-12. https://doi.org/10.1016/0167-4838(95)00185-W

Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase. / Tanaka, Satoshi; Fukui, Tetsuya; Yamamoto, Jun et al.
In: Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, Vol. 1253, No. 1, 15.11.1995, p. 9-12.

Research output: Contribution to journal › Article › peer-review

Tanaka, S, Fukui, T, Yamamoto, J, Shima, YI, Kume, T, Ohgo, M & Ichikawa, A 1995, 'Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase', Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, vol. 1253, no. 1, pp. 9-12. https://doi.org/10.1016/0167-4838(95)00185-W

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AU - Kume, Toshiaki

AU - Ohgo, Makoto

AU - Ichikawa, Atsushi

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Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase

Abstract

Keywords

ASJC Scopus subject areas

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