Prolactin-releasing peptide is essential to maintain the prolactin level and osmotic balance in freshwater teleost fish

Masaaki Fujimoto; Tatsuya Sakamoto; Tomokazu Kanetoh; Michiyo Osaka; Shunsuke Moriyama

doi:10.1016/j.peptides.2005.06.034

Prolactin-releasing peptide is essential to maintain the prolactin level and osmotic balance in freshwater teleost fish

Masaaki Fujimoto, Tatsuya Sakamoto, Tomokazu Kanetoh, Michiyo Osaka, Shunsuke Moriyama

School of Science

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

We administered prolactin-releasing peptide (PrRP) or anti-PrRP antiserum to goldfish in fresh water and analyzed their effects on prolactin and osmoregulatory mechanisms. The pituitary mRNA level of prolactin increased by PrRP but decreased by anti-PrRP. The rate of water inflow in the gills decreased by PrRP and increased by anti-PrRP, showing that PrRP restricts branchial water permeability, as also restricted by prolactin. PrRP also expanded the mucous cell layers on the scales, which may restrict efficiently water inflow by the mucous system. Eventually, the plasma osmotic pressure decreased by anti-PrRP. We conclude that PrRP is essential to maintain prolactin levels and osmotic balance in fresh water.

Original language	English
Pages (from-to)	1104-1109
Number of pages	6
Journal	Peptides
Volume	27
Issue number	5
DOIs	https://doi.org/10.1016/j.peptides.2005.06.034
Publication status	Published - May 2006

Keywords

C-RFa
Chloride cells
Gills
Pituitary
PrRP
Prolactin
mRNA

ASJC Scopus subject areas

Biochemistry
Physiology
Endocrinology
Cellular and Molecular Neuroscience

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10.1016/j.peptides.2005.06.034

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title = "Prolactin-releasing peptide is essential to maintain the prolactin level and osmotic balance in freshwater teleost fish",

abstract = "We administered prolactin-releasing peptide (PrRP) or anti-PrRP antiserum to goldfish in fresh water and analyzed their effects on prolactin and osmoregulatory mechanisms. The pituitary mRNA level of prolactin increased by PrRP but decreased by anti-PrRP. The rate of water inflow in the gills decreased by PrRP and increased by anti-PrRP, showing that PrRP restricts branchial water permeability, as also restricted by prolactin. PrRP also expanded the mucous cell layers on the scales, which may restrict efficiently water inflow by the mucous system. Eventually, the plasma osmotic pressure decreased by anti-PrRP. We conclude that PrRP is essential to maintain prolactin levels and osmotic balance in fresh water.",

keywords = "C-RFa, Chloride cells, Gills, Pituitary, PrRP, Prolactin, mRNA",

author = "Masaaki Fujimoto and Tatsuya Sakamoto and Tomokazu Kanetoh and Michiyo Osaka and Shunsuke Moriyama",

note = "Funding Information: We thank Dr. Manabu Matsuda for providing the cDNA probe encoding goldfish PRL, and Prof. Christopher A. Loretz for his useful comments and critique. This work was supported in part by a grant from the Ministry of Education, Culture, Sports, Science and Technology of Japan and a grant from Takeda Chemical Ind. Ltd. to MF and from Narishige Zoological Science Award to TS. ",

year = "2006",

month = may,

doi = "10.1016/j.peptides.2005.06.034",

language = "English",

volume = "27",

pages = "1104--1109",

journal = "Peptides",

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T1 - Prolactin-releasing peptide is essential to maintain the prolactin level and osmotic balance in freshwater teleost fish

AU - Fujimoto, Masaaki

AU - Sakamoto, Tatsuya

AU - Kanetoh, Tomokazu

AU - Osaka, Michiyo

AU - Moriyama, Shunsuke

N1 - Funding Information: We thank Dr. Manabu Matsuda for providing the cDNA probe encoding goldfish PRL, and Prof. Christopher A. Loretz for his useful comments and critique. This work was supported in part by a grant from the Ministry of Education, Culture, Sports, Science and Technology of Japan and a grant from Takeda Chemical Ind. Ltd. to MF and from Narishige Zoological Science Award to TS.

PY - 2006/5

Y1 - 2006/5

N2 - We administered prolactin-releasing peptide (PrRP) or anti-PrRP antiserum to goldfish in fresh water and analyzed their effects on prolactin and osmoregulatory mechanisms. The pituitary mRNA level of prolactin increased by PrRP but decreased by anti-PrRP. The rate of water inflow in the gills decreased by PrRP and increased by anti-PrRP, showing that PrRP restricts branchial water permeability, as also restricted by prolactin. PrRP also expanded the mucous cell layers on the scales, which may restrict efficiently water inflow by the mucous system. Eventually, the plasma osmotic pressure decreased by anti-PrRP. We conclude that PrRP is essential to maintain prolactin levels and osmotic balance in fresh water.

AB - We administered prolactin-releasing peptide (PrRP) or anti-PrRP antiserum to goldfish in fresh water and analyzed their effects on prolactin and osmoregulatory mechanisms. The pituitary mRNA level of prolactin increased by PrRP but decreased by anti-PrRP. The rate of water inflow in the gills decreased by PrRP and increased by anti-PrRP, showing that PrRP restricts branchial water permeability, as also restricted by prolactin. PrRP also expanded the mucous cell layers on the scales, which may restrict efficiently water inflow by the mucous system. Eventually, the plasma osmotic pressure decreased by anti-PrRP. We conclude that PrRP is essential to maintain prolactin levels and osmotic balance in fresh water.

KW - C-RFa

KW - Chloride cells

KW - Gills

KW - Pituitary

KW - PrRP

KW - Prolactin

KW - mRNA

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DO - 10.1016/j.peptides.2005.06.034

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AN - SCOPUS:33646137400

SN - 0196-9781

VL - 27

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JO - Peptides

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ER -

Prolactin-releasing peptide is essential to maintain the prolactin level and osmotic balance in freshwater teleost fish

Abstract

Keywords

ASJC Scopus subject areas

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