Pyridylsilyl group-driven cross-coupling reactions

Kenichiro Itami, Koichi Mitsudo, Toshiki Nokami, Toshiyuki Kamei, Tooru Koike, Jun ichi Yoshida

Research output: Contribution to journalReview articlepeer-review

28 Citations (Scopus)

Abstract

Summarized herein are the demonstrations that the use of 2-PyMe2Si group as a removable directing group is a powerful strategy for enhancing the efficiency of otherwise sluggish processes and for steering the course of the reaction by taking advantage of attractive substrate-catalyst interaction in the palladium-catalyzed cross-coupling chemistry. The 2-PyMe2Si group-driven Heck-type coupling, Hiyama-type coupling, Stille-type coupling, and allylic alkylation are described.

Original languageEnglish
Pages (from-to)105-113
Number of pages9
JournalJournal of Organometallic Chemistry
Volume653
Issue number1-2
DOIs
Publication statusPublished - Jul 1 2002
Externally publishedYes

Keywords

  • Cross-coupling reaction
  • Pyridylsilyl group
  • Removable directing group

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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