Quantitative analysis of interleukin 6 (IL-6) in patients with IgA nephropathy after tonsillectomy

Yuzo Baba; Hirofumi Akagi; Kunihiro Fukushima; Michiya Kosaka; Kenshi Hattori; Kazunori Nishizaki; Teruhiro Ogawa; Yu Masuda; Kenichi Shikata

doi:10.1016/S0385-8146(98)00047-9

Quantitative analysis of interleukin 6 (IL-6) in patients with IgA nephropathy after tonsillectomy

Yuzo Baba, Hirofumi Akagi, Kunihiro Fukushima, Michiya Kosaka, Kenshi Hattori, Kazunori Nishizaki, Teruhiro Ogawa, Yu Masuda, Kenichi Shikata

University Hospital

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The biological response to tonsillectomy was studied in 21 patients suffering from chronic tonsillitis with or without IgA nephropathy (IgAN). Serum and urinary interleukin-6 (IL-6) levels were measured before and after tonsillectomy. Serum IL-6 levels in case of IgAN peaked 3 h after tonsillectomy and more rapidly than control cases. No significant differences were observed between two cases through the time. Urinary IL-6 levels were significantly higher before and at 6 and 48 h after tonsillectomy in IgAN cases. Stimulation of tonsils caused serum IL-6 elevation and changes in urinary IL-6 levels in IgAN cases. Elevation of urinary IL-6 levels after tonsillectomy in patients with IgAN may reflect an increase in the production of IL-6 in the kidneys. Measurement of urinary IL-6 levels after tonssillectomy is useful to elucidate the efficacy of tonsillectomy in IgAN patients.

Original language	English
Pages (from-to)	177-182
Number of pages	6
Journal	Auris Nasus Larynx
Volume	26
Issue number	2
DOIs	https://doi.org/10.1016/S0385-8146(98)00047-9
Publication status	Published - Apr 1 1999

Keywords

IgA nephropathy
Interleukin-6
Tonsillectomy

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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10.1016/S0385-8146(98)00047-9

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title = "Quantitative analysis of interleukin 6 (IL-6) in patients with IgA nephropathy after tonsillectomy",

abstract = "The biological response to tonsillectomy was studied in 21 patients suffering from chronic tonsillitis with or without IgA nephropathy (IgAN). Serum and urinary interleukin-6 (IL-6) levels were measured before and after tonsillectomy. Serum IL-6 levels in case of IgAN peaked 3 h after tonsillectomy and more rapidly than control cases. No significant differences were observed between two cases through the time. Urinary IL-6 levels were significantly higher before and at 6 and 48 h after tonsillectomy in IgAN cases. Stimulation of tonsils caused serum IL-6 elevation and changes in urinary IL-6 levels in IgAN cases. Elevation of urinary IL-6 levels after tonsillectomy in patients with IgAN may reflect an increase in the production of IL-6 in the kidneys. Measurement of urinary IL-6 levels after tonssillectomy is useful to elucidate the efficacy of tonsillectomy in IgAN patients.",

keywords = "IgA nephropathy, Interleukin-6, Tonsillectomy",

author = "Yuzo Baba and Hirofumi Akagi and Kunihiro Fukushima and Michiya Kosaka and Kenshi Hattori and Kazunori Nishizaki and Teruhiro Ogawa and Yu Masuda and Kenichi Shikata",

year = "1999",

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doi = "10.1016/S0385-8146(98)00047-9",

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T1 - Quantitative analysis of interleukin 6 (IL-6) in patients with IgA nephropathy after tonsillectomy

AU - Baba, Yuzo

AU - Akagi, Hirofumi

AU - Fukushima, Kunihiro

AU - Kosaka, Michiya

AU - Hattori, Kenshi

AU - Nishizaki, Kazunori

AU - Ogawa, Teruhiro

AU - Masuda, Yu

AU - Shikata, Kenichi

PY - 1999/4/1

Y1 - 1999/4/1

N2 - The biological response to tonsillectomy was studied in 21 patients suffering from chronic tonsillitis with or without IgA nephropathy (IgAN). Serum and urinary interleukin-6 (IL-6) levels were measured before and after tonsillectomy. Serum IL-6 levels in case of IgAN peaked 3 h after tonsillectomy and more rapidly than control cases. No significant differences were observed between two cases through the time. Urinary IL-6 levels were significantly higher before and at 6 and 48 h after tonsillectomy in IgAN cases. Stimulation of tonsils caused serum IL-6 elevation and changes in urinary IL-6 levels in IgAN cases. Elevation of urinary IL-6 levels after tonsillectomy in patients with IgAN may reflect an increase in the production of IL-6 in the kidneys. Measurement of urinary IL-6 levels after tonssillectomy is useful to elucidate the efficacy of tonsillectomy in IgAN patients.

AB - The biological response to tonsillectomy was studied in 21 patients suffering from chronic tonsillitis with or without IgA nephropathy (IgAN). Serum and urinary interleukin-6 (IL-6) levels were measured before and after tonsillectomy. Serum IL-6 levels in case of IgAN peaked 3 h after tonsillectomy and more rapidly than control cases. No significant differences were observed between two cases through the time. Urinary IL-6 levels were significantly higher before and at 6 and 48 h after tonsillectomy in IgAN cases. Stimulation of tonsils caused serum IL-6 elevation and changes in urinary IL-6 levels in IgAN cases. Elevation of urinary IL-6 levels after tonsillectomy in patients with IgAN may reflect an increase in the production of IL-6 in the kidneys. Measurement of urinary IL-6 levels after tonssillectomy is useful to elucidate the efficacy of tonsillectomy in IgAN patients.

KW - IgA nephropathy

KW - Interleukin-6

KW - Tonsillectomy

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Quantitative analysis of interleukin 6 (IL-6) in patients with IgA nephropathy after tonsillectomy

Abstract

Keywords

ASJC Scopus subject areas

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