Abstract
Effects of cepharanthine and alpha-tocopherol on radiation-induced peroxidation of lipids dissolved in methanol(MeOH)-chloroform (CHCl3)-H2O(v/v, 2/1/0.8) were examined. alpha-Tocopherol strongly inhibited radiation-induced peroxidation of lipids dissolved in MeOH-CHCl3-H2O. However, cepharanthine exhibited a weak inhibitory action in this system. The change in the absorption spectrum of alpha-tocopherol and cepharanthine by X-irradiation was measured. The reagents were dissolved in 95% EtOH acidified with 20 mM HCl and in MeOH-CHCl3-H2O. alpha-Tocopherol exhibited the change in its absorption spectrum in both systems, and seemed to be oxidized at a high rate by free radicals. However, cepharanthine slightly exhibited the change in its spectrum in MeOH-CHCl3-H2O, but not in acidified EtOH.
| Original language | English |
|---|---|
| Pages (from-to) | 243-246 |
| Number of pages | 4 |
| Journal | Physiological chemistry and physics and medical NMR |
| Volume | 17 |
| Issue number | 3 |
| Publication status | Published - 1985 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Physiology
- Spectroscopy