Radiologic removal and replacement of port-catheter systems for hepatic arterial infusion chemotherapy

Toshihiro Iguchi, Yoshitaka Inaba, Yasuaki Arai, Hidekazu Yamaura, Yozo Sato, Masaya Miyazaki, Hiroshi Shimamoto, Takayuki Hayashi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


OBJECTIVE. The purpose of our study was to retrospectively evaluate the safety and efficacy of radiologic removal and replacement of port-catheter systems. MATERIALS AND METHODS. Between January 1999 and December 2004, 532 patients with unresectable advanced liver cancer underwent radiologic placement of port-catheter systems at our institution. Of these, 18 patients (nine men and nine women; age range, 32-83 years; mean age, 53.8 years) underwent removal of an implanted port-catheter system via the right femoral artery and radiographically guided replacement with a new system to allow continuous hepatic arterial infusion chemotherapy; we retrospectively reviewed these 18 cases. The reasons for removal of the previously implanted systems were as follows: catheter dislodgement (n = 15), catheter obstruction (n = 1), infection related to the implanted port (n = 1), and hemodynamic change (n = 1). Digital subtraction angiography and CT were performed, usually during injection of contrast medium through the implanted port-catheter system, within a few days after the replacement procedure and every 3 months thereafter. RESULTS. We successfully performed radiologic removal and replacement of the port-catheter system while the patient was under local anesthesia in all 18 patients without complications requiring treatment. The cumulative patency rates of the hepatic artery after removal of the old port-catheter system and replacement with a new port-catheter system were 87.8% and 64.1% at 6 months and 1 year, respectively. Hepatic arterial infusion chemotherapy after replacement was performed 0-68 times (median, 19 times). CONCLUSION. When an implanted port-catheter system can no longer be used but the patency of the hepatic artery is confirmed and continuous hepatic arterial infusion chemotherapy is required, removal and replacement of the port-catheter system are recommended.

Original languageEnglish
Pages (from-to)1579-1584
Number of pages6
JournalAmerican Journal of Roentgenology
Issue number6
Publication statusPublished - Dec 1 2006
Externally publishedYes


  • Chemotherapy
  • Implantable devices
  • Liver cancer
  • Port-catheter system

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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