Radiotherapy for oral cancer

Toshihiko Takenobu, Jun ichi Asaumi, Hidenobu Matsuzaki, Marina Hara, Mistuhiro Takemoto, Kuniaki Katsui, Masahiro Kuroda, Susumu Kanazawa

Research output: Chapter in Book/Report/Conference proceedingChapter


Oral cancers occur at a relatively high rate in elderly patients. However, elderly patients often cannot undergo general anesthetization or surgery due to their declining physical condition. In addition, elderly patients who do undergo surgery for oral cancer occasionally develop problems with eating and swallowing or infectious disease. At the same time, oral cancers have been on the rise among patients in their 20s and 30s. For these younger patients, the aesthetic appearance of the oral region, as well as the full preservation of the abilities to eat, swallow, and enunciate, are especially important. Thus, in both elderly and younger patients, the preservation of aesthetic features and oral functions is critical when treating oral cancers. Conservative oral cancer treatment approaches include radiotherapy, chemotherapy, thermotherapy, immunotherapy, and gene therapy. In oral cancer cases in which surgery is not appropriate and a more conservative treatment must be used, radiotherapy is the most frequently chosen approach. Brachytherapy is often applied in early stage (stage I and II) and chemoradiotherapy in advanced stage (stage III and IV) oral cancers.The first part of this chapter presents the general method of radiotherapy for oral cancer and its potential side effects. The second portion of the chapter addresses the subject of brachytherapy, including low-dose rate and high-dose rate brachytherapy and mold therapy, and chemoradiotherapy.

Original languageEnglish
Title of host publicationOral Cancer
Subtitle of host publicationCauses, Diagnosis and Treatment
PublisherNova Science Publishers, Inc.
Number of pages34
ISBN (Print)9781612093055
Publication statusPublished - Apr 2011

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Medicine


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