Randomized controlled trial of epidural versus patient-controlled intravenous analgesia for postoperative pain control after laparoscopic gastrectomy

Satoru Kikuchi; Shinji Kuroda; Masahiko Nishizaki; Takashi Matsusaki; Toshiharu Mitsuhashi; Kazuya Kuwada; Shunsuke Kagawa; Hiroshi Morimatsu; Toshiyoshi Fujiwara

Randomized controlled trial of epidural versus patient-controlled intravenous analgesia for postoperative pain control after laparoscopic gastrectomy

Satoru Kikuchi, Shinji Kuroda, Masahiko Nishizaki, Takashi Matsusaki, Toshiharu Mitsuhashi, Kazuya Kuwada, Shunsuke Kagawa, Hiroshi Morimatsu, Toshiyoshi Fujiwara

Research output: Contribution to journal › Article › peer-review

Abstract

Although epidural analgesia (EDA) is considered standard postoperative analgesia for open gastrectomy, it has been unclear whether EDA has benefits in laparoscopic gastrectomy (LG) because postoperative pain after a laparoscopic procedure is significantly reduced. We are conducting a two-arm, single-center, prospective randomized non-inferiority trial to evaluate the postoperative pain relief of patient-controlled intravenous analgesia (PCIA) compared to EDA. A total of 132 patients undergoing LG will be randomized to EDA and PCIA groups (n=64 each) for postoperative pain control. The primary endpoint is postoperative pain at 24 h after surgery. This study will clarify the optimal pain management after LG.

Original language	English
Pages (from-to)	95-98
Number of pages	4
Journal	Acta medica Okayama
Volume	72
Issue number	1
Publication status	Published - 2018

Keywords

Epidural analgesia
Laparoscopic gastrectomy
Pain relief
Patient-controlled intravenous analgesia

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "Randomized controlled trial of epidural versus patient-controlled intravenous analgesia for postoperative pain control after laparoscopic gastrectomy",

abstract = "Although epidural analgesia (EDA) is considered standard postoperative analgesia for open gastrectomy, it has been unclear whether EDA has benefits in laparoscopic gastrectomy (LG) because postoperative pain after a laparoscopic procedure is significantly reduced. We are conducting a two-arm, single-center, prospective randomized non-inferiority trial to evaluate the postoperative pain relief of patient-controlled intravenous analgesia (PCIA) compared to EDA. A total of 132 patients undergoing LG will be randomized to EDA and PCIA groups (n=64 each) for postoperative pain control. The primary endpoint is postoperative pain at 24 h after surgery. This study will clarify the optimal pain management after LG.",

keywords = "Epidural analgesia, Laparoscopic gastrectomy, Pain relief, Patient-controlled intravenous analgesia",

author = "Satoru Kikuchi and Shinji Kuroda and Masahiko Nishizaki and Takashi Matsusaki and Toshiharu Mitsuhashi and Kazuya Kuwada and Shunsuke Kagawa and Hiroshi Morimatsu and Toshiyoshi Fujiwara",

note = "Funding Information: The authors thank Professor Shiro Hinotsu at the Center for Innovative Clinical Medicine, Okayama University Hospital for his considerable assistance in writing this protocol. Publisher Copyright: {\textcopyright} 2018 by Okayama University Medical School.",

year = "2018",

language = "English",

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journal = "Acta medica Okayama",

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T1 - Randomized controlled trial of epidural versus patient-controlled intravenous analgesia for postoperative pain control after laparoscopic gastrectomy

AU - Kikuchi, Satoru

AU - Kuroda, Shinji

AU - Nishizaki, Masahiko

AU - Matsusaki, Takashi

AU - Mitsuhashi, Toshiharu

AU - Kuwada, Kazuya

AU - Kagawa, Shunsuke

AU - Morimatsu, Hiroshi

AU - Fujiwara, Toshiyoshi

N1 - Funding Information: The authors thank Professor Shiro Hinotsu at the Center for Innovative Clinical Medicine, Okayama University Hospital for his considerable assistance in writing this protocol. Publisher Copyright: © 2018 by Okayama University Medical School.

PY - 2018

Y1 - 2018

N2 - Although epidural analgesia (EDA) is considered standard postoperative analgesia for open gastrectomy, it has been unclear whether EDA has benefits in laparoscopic gastrectomy (LG) because postoperative pain after a laparoscopic procedure is significantly reduced. We are conducting a two-arm, single-center, prospective randomized non-inferiority trial to evaluate the postoperative pain relief of patient-controlled intravenous analgesia (PCIA) compared to EDA. A total of 132 patients undergoing LG will be randomized to EDA and PCIA groups (n=64 each) for postoperative pain control. The primary endpoint is postoperative pain at 24 h after surgery. This study will clarify the optimal pain management after LG.

AB - Although epidural analgesia (EDA) is considered standard postoperative analgesia for open gastrectomy, it has been unclear whether EDA has benefits in laparoscopic gastrectomy (LG) because postoperative pain after a laparoscopic procedure is significantly reduced. We are conducting a two-arm, single-center, prospective randomized non-inferiority trial to evaluate the postoperative pain relief of patient-controlled intravenous analgesia (PCIA) compared to EDA. A total of 132 patients undergoing LG will be randomized to EDA and PCIA groups (n=64 each) for postoperative pain control. The primary endpoint is postoperative pain at 24 h after surgery. This study will clarify the optimal pain management after LG.

KW - Epidural analgesia

KW - Laparoscopic gastrectomy

KW - Pain relief

KW - Patient-controlled intravenous analgesia

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Randomized controlled trial of epidural versus patient-controlled intravenous analgesia for postoperative pain control after laparoscopic gastrectomy

Abstract

Keywords

ASJC Scopus subject areas

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