Rapidly Progressive Stenosis of the Left Main Trunk Ostium Starting 21 Months After Stent Implantation

Yoichiro Naito, Masaki Yoshikawa, Kazufumi Nakamura, Motoki Kubo, Hiroyasu Sugiyama, Hideyuki Suzuki, Shinpei Fujita, Yasunori Arai, Sho Takahashi, Yuichi Kato, Yu Yoshida, Hiroaki Akai, Shuhei Murakami, Hiroshi Ito

Research output: Contribution to journalArticlepeer-review


Rapidly progressive in-stent restenosis (ISR) after stent deployment from the left main trunk (LMT) to the left anterior descending artery (LAD) without plaque at the LMT ostium has not been reported. A 60-year-old Japanese man with a history of scleroderma, pulmonary fibrosis, and type 2 diabetes developed acute myocardial infarction of the right coronary artery (RCA) and was treated by emergency percutaneous coronary intervention (PCI) for RCA. Nine days later he underwent PCI from the LMT to the LAD. Follow-up coronary angiography (CAG) at 9 and 21 months post-PCI did not reveal ISR in any lesion, but the patient experienced cardiac arrest at 25 months post-PCI. Emergency CAG after resuscitation revealed ISR of the LMT ostium; emergency PCI was conducted. The development of ISR at the ostium of the LMT although the patient was free of plaque 4 months before is extremely unusual.

Original languageEnglish
Pages (from-to)99-104
Number of pages6
JournalActa medica Okayama
Issue number1
Publication statusPublished - 2022


  • Cardiopulmonary arrest
  • In-stent restenosis
  • Left main trunk

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology


Dive into the research topics of 'Rapidly Progressive Stenosis of the Left Main Trunk Ostium Starting 21 Months After Stent Implantation'. Together they form a unique fingerprint.

Cite this