Abstract
Recent basic and clinical research has revealed that hydrogen is an important physiological regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen dissolved in water and injection with hydrogen-saturated saline. This review summarizes currently available data regarding the protective role of hydrogen, provides an outline of recent advances in research on the use of hydrogen as a therapeutic medical gas in diverse models of disease and discusses the feasibility of hydrogen as a therapeutic strategy. It is not an overstatement to say that hydrogen's impact on therapeutic and preventive medicine could be enormous in the future.
| Original language | English |
|---|---|
| Pages (from-to) | 971-982 |
| Number of pages | 12 |
| Journal | Free Radical Research |
| Volume | 44 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sept 1 2010 |
| Externally published | Yes |
Keywords
- Molecular hydrogen
- antioxidant therapy
- radical oxygen species
ASJC Scopus subject areas
- Biochemistry