Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system

Manabu Kuroboshi; Toshihito Kita; Asuka Aono; Toshimasa Katagiri; Seiya Kikuchi; Syoko Yamane; Hiromu Kawakubo; Hideo Tanaka

doi:10.1016/j.tetlet.2014.12.132

Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me₃SiCl/DMI system

Manabu Kuroboshi
, Toshihito Kita
, Asuka Aono
, Toshimasa Katagiri
, Seiya Kikuchi
, Syoko Yamane
, Hiromu Kawakubo
, Hideo Tanaka

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me₃SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.

Original language	English
Pages (from-to)	918-920
Number of pages	3
Journal	Tetrahedron Letters
Volume	56
Issue number	7
DOIs	https://doi.org/10.1016/j.tetlet.2014.12.132
Publication status	Published - Feb 11 2015

Keywords

1,3-Dimethyl-2-imidazolidinone
Magnesium
Phosphine
Phosphine oxide
Reduction

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2014.12.132

Cite this

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title = "Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system",

abstract = "Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me3SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.",

keywords = "1,3-Dimethyl-2-imidazolidinone, Magnesium, Phosphine, Phosphine oxide, Reduction",

author = "Manabu Kuroboshi and Toshihito Kita and Asuka Aono and Toshimasa Katagiri and Seiya Kikuchi and Syoko Yamane and Hiromu Kawakubo and Hideo Tanaka",

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T1 - Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system

AU - Kuroboshi, Manabu

AU - Kita, Toshihito

AU - Aono, Asuka

AU - Katagiri, Toshimasa

AU - Kikuchi, Seiya

AU - Yamane, Syoko

AU - Kawakubo, Hiromu

AU - Tanaka, Hideo

PY - 2015/2/11

Y1 - 2015/2/11

N2 - Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me3SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.

AB - Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me3SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.

KW - 1,3-Dimethyl-2-imidazolidinone

KW - Magnesium

KW - Phosphine

KW - Phosphine oxide

KW - Reduction

UR - https://www.scopus.com/pages/publications/84921634420

UR - https://www.scopus.com/pages/publications/84921634420#tab=citedBy

U2 - 10.1016/j.tetlet.2014.12.132

DO - 10.1016/j.tetlet.2014.12.132

M3 - Article

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SN - 0040-4039

VL - 56

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EP - 920

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -