Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation

Yumi Inukai Motokura; Hisao Higo; Chiaki Matsumoto; Mari Uno; Kanako Fujiwara; Toshiki Terao; Satoko Makimoto; Fumiyo Higaki; Ken ichi Matsuoka; Fumiaki Tokioka; Yoshinobu Maeda; Nobuaki Miyahara

doi:10.1016/j.resinv.2024.06.007

Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation

Yumi Inukai Motokura, Hisao Higo, Chiaki Matsumoto, Mari Uno, Kanako Fujiwara, Toshiki Terao, Satoko Makimoto, Fumiyo Higaki, Ken ichi Matsuoka, Fumiaki Tokioka, Yoshinobu Maeda, Nobuaki Miyahara

Research output: Contribution to journal › Article › peer-review

Abstract

A 50-year-old man was diagnosed with hypersensitivity pneumonitis caused by the environment of his bar owing to worsening symptoms, laboratory test results, and computed tomography images after an environmental inhalation challenge test. His hypersensitivity pneumonitis exacerbated despite receiving prednisolone 20 mg/day. The patient underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched unrelated donor for myelodysplastic syndrome. No exacerbation of hypersensitivity pneumonitis was observed after HSCT. An environmental inhalation challenge test involving exposure to his bar confirmed the remission of hypersensitivity pneumonitis after HSCT. This case demonstrates that hypersensitivity pneumonitis can be remitted by HSCT.

Original language	English
Pages (from-to)	759-761
Number of pages	3
Journal	Respiratory Investigation
Volume	62
Issue number	5
DOIs	https://doi.org/10.1016/j.resinv.2024.06.007
Publication status	Published - Sept 2024
Externally published	Yes

Keywords

Allogeneic hematopoietic stem cell transplantation
Environmental inhalation challenge test
Hypersensitivity pneumonitis
Myelodysplastic syndrome

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

Access to Document

10.1016/j.resinv.2024.06.007

Cite this

@article{3be53fb24ce24497a31c5d85761c49d2,

title = "Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation",

abstract = "A 50-year-old man was diagnosed with hypersensitivity pneumonitis caused by the environment of his bar owing to worsening symptoms, laboratory test results, and computed tomography images after an environmental inhalation challenge test. His hypersensitivity pneumonitis exacerbated despite receiving prednisolone 20 mg/day. The patient underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched unrelated donor for myelodysplastic syndrome. No exacerbation of hypersensitivity pneumonitis was observed after HSCT. An environmental inhalation challenge test involving exposure to his bar confirmed the remission of hypersensitivity pneumonitis after HSCT. This case demonstrates that hypersensitivity pneumonitis can be remitted by HSCT.",

keywords = "Allogeneic hematopoietic stem cell transplantation, Environmental inhalation challenge test, Hypersensitivity pneumonitis, Myelodysplastic syndrome",

author = "{Inukai Motokura}, Yumi and Hisao Higo and Chiaki Matsumoto and Mari Uno and Kanako Fujiwara and Toshiki Terao and Satoko Makimoto and Fumiyo Higaki and Matsuoka, {Ken ichi} and Fumiaki Tokioka and Yoshinobu Maeda and Nobuaki Miyahara",

note = "Publisher Copyright: {\textcopyright} 2024",

year = "2024",

month = sep,

doi = "10.1016/j.resinv.2024.06.007",

language = "English",

volume = "62",

pages = "759--761",

journal = "Respiratory Investigation",

issn = "2212-5345",

publisher = "Elsevier B.V.",

number = "5",

}

TY - JOUR

T1 - Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation

AU - Inukai Motokura, Yumi

AU - Higo, Hisao

AU - Matsumoto, Chiaki

AU - Uno, Mari

AU - Fujiwara, Kanako

AU - Terao, Toshiki

AU - Makimoto, Satoko

AU - Higaki, Fumiyo

AU - Matsuoka, Ken ichi

AU - Tokioka, Fumiaki

AU - Maeda, Yoshinobu

AU - Miyahara, Nobuaki

PY - 2024/9

Y1 - 2024/9

N2 - A 50-year-old man was diagnosed with hypersensitivity pneumonitis caused by the environment of his bar owing to worsening symptoms, laboratory test results, and computed tomography images after an environmental inhalation challenge test. His hypersensitivity pneumonitis exacerbated despite receiving prednisolone 20 mg/day. The patient underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched unrelated donor for myelodysplastic syndrome. No exacerbation of hypersensitivity pneumonitis was observed after HSCT. An environmental inhalation challenge test involving exposure to his bar confirmed the remission of hypersensitivity pneumonitis after HSCT. This case demonstrates that hypersensitivity pneumonitis can be remitted by HSCT.

AB - A 50-year-old man was diagnosed with hypersensitivity pneumonitis caused by the environment of his bar owing to worsening symptoms, laboratory test results, and computed tomography images after an environmental inhalation challenge test. His hypersensitivity pneumonitis exacerbated despite receiving prednisolone 20 mg/day. The patient underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched unrelated donor for myelodysplastic syndrome. No exacerbation of hypersensitivity pneumonitis was observed after HSCT. An environmental inhalation challenge test involving exposure to his bar confirmed the remission of hypersensitivity pneumonitis after HSCT. This case demonstrates that hypersensitivity pneumonitis can be remitted by HSCT.

KW - Allogeneic hematopoietic stem cell transplantation

KW - Environmental inhalation challenge test

KW - Hypersensitivity pneumonitis

KW - Myelodysplastic syndrome

UR - http://www.scopus.com/inward/record.url?scp=85197035977&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85197035977&partnerID=8YFLogxK

U2 - 10.1016/j.resinv.2024.06.007

DO - 10.1016/j.resinv.2024.06.007

M3 - Article

C2 - 38959673

AN - SCOPUS:85197035977

SN - 2212-5345

VL - 62

SP - 759

EP - 761

JO - Respiratory Investigation

JF - Respiratory Investigation

IS - 5

ER -

Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this