Repair roles of hSMUG1 assessed by damage specificity and cellular activity.

Aya Masaoka, Mayumi Matsubara, Tamon Tanaka, Hiroaki Terato, Yoshihiko Ohyama, Kihei Kubo, Hiroshi Ide

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Single-strand-selective monofunctional uracil-DNA glycosylase (SMUG1) was previously identified as a putative backup enzyme of major mammalian uracil-DNA glycosylase (UDG). However, the subsequent studies have shown conflicting results about the substrate specificity of SMUG1. In the present study, to clarify the repair role of SMUG1, we determined the damage specificity of purified human SMUG1 (hSMUG1) and its contribution to repair of oxidized bases in HeLa cell extracts.

Original languageEnglish
Pages (from-to)263-264
Number of pages2
JournalNucleic acids research. Supplement (2001)
Issue number3
Publication statusPublished - 2003
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Repair roles of hSMUG1 assessed by damage specificity and cellular activity.'. Together they form a unique fingerprint.

Cite this