Reticalmin: A novel calcium-calmodulin-dependent protein kinase IV-like protein in rat retina

Kazuyuki Hirooka, Masaaki Tokuda, Toyohiro Tsumura, Bushra Y. Ahmed, Toshifumi Itano, Hideki Matsui, Ryoji Konishi, Eiichi Hasegawa, Sachiko Okuno, Takako Kitani, Hitoshi Fujisawa, Osamu Hatase

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Western blot analysis of 100,000g supernatant of rat retina using a polyclonal anti-Ca2+/calmodulin-dependent protein kinase IV (CaM-kinase IV) antibody revealed an immunoreactive mass of 35 kDa, termed reticalmin. Lower amount of a isoform of CaM-kinase IV was also expressed in rat retina. Reticalmin did not react with anti-CaM-kinase IV C-terminal peptide antibody which recognized α and β isoforms of CaM-kinase IV and calspermin. Immunohistochemically reticalmin was shown to be localized mainly in the outer segment of photo-receptor cells, and in dendrites of inner plexiform layers and may be in nuclei of ganglion cells and some inner nuclear layer cells.

Original languageEnglish
Pages (from-to)2029-2033
Number of pages5
JournalVision Research
Issue number15
Publication statusPublished - Aug 1997


  • Ca-calmodulin-dependent protein kinase IV
  • Reticalmin
  • Retina

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems


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