Revised criteria for the early diagnosis of diabetic nephropathy

Shigeki Inomata, Masakazu Haneda, Tatsumi Moriya, Shigehiro Katayama, Yasuhiko Iwamoto, Hideto Sakai, Yasuhiko Tomino, Seiichi Matsuo, Yasushi Asano, Hirofumi Makino

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13 Citations (Scopus)


The Diabetic Nephropathy Committee recommends the use of revised criteria for the early diagnosis of diabetic nephropathy in Japan. The new criteria are as follows: 1) Urinary albumin should be determined by immunoassay using a morning spot urine sample in diabetic patients without proteinuria or with dipstick-positive (+1) proteinuria. 2) A urinary albumin-to-creatinine ratio ranging from 30 to 299 mg/ gCr in 2 or more of 3 specimens may be diagnosed as microalbuminuria. 3) Two alternatives, i.e. the urinary albumin excretion rate of 30∼299 mg/24hr in 24hr urine collection or 20∼199 μg/min in timed urine collection can be used to detect microalbuminuria. 4) Renal hypertrophy and elevated urinary type IV collagen may indicate the existence of diabetic renal disease. 5) Microalbuminuria originating in non-diabetic diseases should be excluded.

Original languageEnglish
Pages (from-to)767-769
Number of pages3
JournalJapanese Journal of Nephrology
Issue number7
Publication statusPublished - Dec 7 2005
Externally publishedYes

ASJC Scopus subject areas

  • Nephrology


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