TY - JOUR
T1 - Risk factors for elevated intraocular pressure after trans-tenon retrobulbar injections of triamcinolone
AU - Hirooka, Kazuyuki
AU - Shiraga, Fumio
AU - Tanaka, Shigeto
AU - Baba, Tetsuya
AU - Mandai, Hiroshi
PY - 2006/5
Y1 - 2006/5
N2 - Purpose: To determine the risk factors that induce an elevation of intraocular pressure (IOP) after trans-Tenon retrobulbar injections of triamcinolone acetonide. Methods: We retrospectively reviewed the medical records of 49 consecutive patients (49 eyes) with choroidal neovascularization or diffuse diabetic macular edema who had received one trans-Tenon retrobulbar injection of triamcinolone acetonide (20 mg) between June 2003 and September 2004, while being treated at Kagawa University Hospital or Okayama Saiseikai General Hospital. Diabetes mellitus had been diagnosed in ten of the patients. Steroid responders were defined as having a relative increase in intraocular pressure (IOP) of >6 mmHg and an absolute IOP >20 mmHg with an anatomically open anterior chamber angle. The mean follow-up time was 4.2 ± 0.2 months (range, 3-6 months). Results: Nine patients were responders and 40 patients were nonresponders. The elevation of the IOP occurred 1 to 4 weeks after the injection. The only preoperative predictive factor for the steroid responders was the presence of diabetes mellitus (multiple logistic regression analysis, odds ratio = 32.78, P = 0.006). After topical glaucoma medication, the IOP returned to acceptable levels in all responders. Conclusions: Our results suggest an association between diabetes mellitus and elevated IOP after a trans-Tenon retrobulbar triamcinolone acetonide injection.
AB - Purpose: To determine the risk factors that induce an elevation of intraocular pressure (IOP) after trans-Tenon retrobulbar injections of triamcinolone acetonide. Methods: We retrospectively reviewed the medical records of 49 consecutive patients (49 eyes) with choroidal neovascularization or diffuse diabetic macular edema who had received one trans-Tenon retrobulbar injection of triamcinolone acetonide (20 mg) between June 2003 and September 2004, while being treated at Kagawa University Hospital or Okayama Saiseikai General Hospital. Diabetes mellitus had been diagnosed in ten of the patients. Steroid responders were defined as having a relative increase in intraocular pressure (IOP) of >6 mmHg and an absolute IOP >20 mmHg with an anatomically open anterior chamber angle. The mean follow-up time was 4.2 ± 0.2 months (range, 3-6 months). Results: Nine patients were responders and 40 patients were nonresponders. The elevation of the IOP occurred 1 to 4 weeks after the injection. The only preoperative predictive factor for the steroid responders was the presence of diabetes mellitus (multiple logistic regression analysis, odds ratio = 32.78, P = 0.006). After topical glaucoma medication, the IOP returned to acceptable levels in all responders. Conclusions: Our results suggest an association between diabetes mellitus and elevated IOP after a trans-Tenon retrobulbar triamcinolone acetonide injection.
KW - Diabetes mellitus
KW - Intraocular pressure
KW - Risk factor
KW - Steroid responder
KW - Triamcinolone acetonide
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U2 - 10.1007/s10384-005-0306-9
DO - 10.1007/s10384-005-0306-9
M3 - Article
C2 - 16767378
AN - SCOPUS:33745085565
SN - 0021-5155
VL - 50
SP - 235
EP - 238
JO - Japanese Journal of Ophthalmology
JF - Japanese Journal of Ophthalmology
IS - 3
ER -
