TY - JOUR
T1 - Roseomonas mucosa bacteremia in a neutropenic child
T2 - A case report and literature review
AU - Kimura, Keigo
AU - Hagiya, Hideharu
AU - Nishi, Isao
AU - Yoshida, Hisao
AU - Tomono, Kazunori
N1 - Funding Information:
This study was supported by the Center for Medical Research and Education, Graduate School of Medicine, Osaka University . We would like to thank enago ( www.enago.jp/ ) for English language editing.
Publisher Copyright:
© 2018
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Roseomonas species is rarely found to be pathogenic to humans and there are few clinical cases that have been described in the literature. We report a case of Roseomonas mucosa bacteremia that involved a 9-year-old Japanese boy who was in a condition of febrile neutropenia caused by chemotherapy for cerebellar medulloblastoma. Conventional phenotyping failed to identify the organism; however, genetic analysis using 16S rDNA sequencing confirmed the pathogen to be R. mucosa. The patient recovered following treatment by meropenem without any complications. A literature review of pediatric cases of Roseomonas bacteremia identified 12 other documented cases, and these revealed that a common clinical situation for the infection is an immunocompromised state with malignancy and/or an indwelling intravenous catheter. Because of the low number of cases, the overall picture of Roseomonas bacteremia in children remains to be elucidated; however, the prognosis of the infection appears to be satisfactory.
AB - Roseomonas species is rarely found to be pathogenic to humans and there are few clinical cases that have been described in the literature. We report a case of Roseomonas mucosa bacteremia that involved a 9-year-old Japanese boy who was in a condition of febrile neutropenia caused by chemotherapy for cerebellar medulloblastoma. Conventional phenotyping failed to identify the organism; however, genetic analysis using 16S rDNA sequencing confirmed the pathogen to be R. mucosa. The patient recovered following treatment by meropenem without any complications. A literature review of pediatric cases of Roseomonas bacteremia identified 12 other documented cases, and these revealed that a common clinical situation for the infection is an immunocompromised state with malignancy and/or an indwelling intravenous catheter. Because of the low number of cases, the overall picture of Roseomonas bacteremia in children remains to be elucidated; however, the prognosis of the infection appears to be satisfactory.
KW - Bloodstream infection
KW - Febrile neutropenia
KW - Roseomonas mucosa
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U2 - 10.1016/j.idcr.2018.e00469
DO - 10.1016/j.idcr.2018.e00469
M3 - Article
AN - SCOPUS:85056574256
SN - 2214-2509
VL - 14
JO - IDCases
JF - IDCases
M1 - e00469
ER -
