Scoliosis in patients with severe cerebral palsy: Three different courses in adolescents

Yoshiaki Oda, Tomoyuki Takigawa, Yoshihisa Sugimoto, Masato Tanaka, Hirofumi Akazawa, Toshifumi Ozaki

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Patients with cerebral palsy (CP) frequently present with scoliosis; however, the pattern of curve progression is difficult to predict. We aimed to clarify the natural course of the progression of scoliosis and to identify scoliosis predictors. This was a retrospective, single-center, observational study. Total of 92 CP patients from Asahikawasou Ryouiku Iryou Center in Okayama, Japan were retrospectively analyzed. Cobb angle, presence of hip dislocation and pelvic obliquity, and Gross Motor Function Classification System (GMFCS) were investigated. Severe CP was defined as GMFCS level IV or V. The mean observation period was 10.7 years. Thirtyfour severe CP patients presented with scoliosis and were divided into 3 groups based on their clinical courses: severe, moderate and mild. The mean Cobb angles at the final follow-up were 129°, 53°, and 13° in the severe, moderate, and mild groups, respectively. The average progressions from 18 to 25 years were 2.7°/year, 0.7°/year, and 0.1°/year in the severe, moderate, and mild curve groups, respectively. We observed the natural course of scoliosis and identified 3 courses based on the Cobb angle at 15 and 18 years of age. This method of classification may help clinicians predict the patients' disease progression.

Original languageEnglish
Pages (from-to)119-126
Number of pages8
JournalActa medica Okayama
Issue number2
Publication statusPublished - 2017


  • Cobb angle
  • Natural course
  • Progression
  • Scoliosis
  • Severe cerebral palsy

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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