Seborrheic dermatitis-like eruption following interleukin-2 administration

Yoshio Kawakami, Taeko Nakamura-Wakatsuki, Toshiyuki Yamamoto

Research output: Contribution to journalLetterpeer-review

5 Citations (Scopus)


We describe a 72-year-old man suffering from renal cell carcinoma with lung metastases who developed scaly erythema on his face after the administration of recombinant interleukin-2 (rIL-2). A skin biopsy revealed intraepidermal and superficial perivascular infiltrate of mononuclear cells that were mainly composed of CD3 positive T-cells. There have been two cases of seborrheic dermatitis-like eruption induced by rIL-2. However, neither of them had histopathological evaluation. To our knowledge, this is the first case of seborrheic dermatitis-like eruption following rIL-2 administration whose histopathological investigations were performed.

Original languageEnglish
JournalDermatology Online Journal
Issue number9
Publication statusPublished - Sept 1 2010
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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