Selective cleavage of primary MPM ethers with TMSI/Et3N

Isao Kadota; Yuji Yamagami; Naoya Fujita; Hiroyoshi Takamura

doi:10.1016/j.tetlet.2009.05.084

Selective cleavage of primary MPM ethers with TMSI/Et₃N

Isao Kadota, Yuji Yamagami, Naoya Fujita, Hiroyoshi Takamura

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A useful method for the selective cleavage of primary MPM ethers by using TMSI/Et₃N is described. Other protective groups such as secondary MPM ethers, silyl ethers, and benzylidene acetal were stable under the reaction conditions.

Original language	English
Pages (from-to)	4552-4553
Number of pages	2
Journal	Tetrahedron Letters
Volume	50
Issue number	31
DOIs	https://doi.org/10.1016/j.tetlet.2009.05.084
Publication status	Published - Aug 5 2009

Keywords

Deprotection
MPM ether
Selective cleavage
TMSI

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2009.05.084

Cite this

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title = "Selective cleavage of primary MPM ethers with TMSI/Et3N",

abstract = "A useful method for the selective cleavage of primary MPM ethers by using TMSI/Et3N is described. Other protective groups such as secondary MPM ethers, silyl ethers, and benzylidene acetal were stable under the reaction conditions.",

keywords = "Deprotection, MPM ether, Selective cleavage, TMSI",

author = "Isao Kadota and Yuji Yamagami and Naoya Fujita and Hiroyoshi Takamura",

note = "Funding Information: This work was financially supported by the Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan.",

year = "2009",

month = aug,

day = "5",

doi = "10.1016/j.tetlet.2009.05.084",

language = "English",

volume = "50",

pages = "4552--4553",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Selective cleavage of primary MPM ethers with TMSI/Et3N

AU - Kadota, Isao

AU - Yamagami, Yuji

AU - Fujita, Naoya

AU - Takamura, Hiroyoshi

N1 - Funding Information: This work was financially supported by the Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan.

PY - 2009/8/5

Y1 - 2009/8/5

N2 - A useful method for the selective cleavage of primary MPM ethers by using TMSI/Et3N is described. Other protective groups such as secondary MPM ethers, silyl ethers, and benzylidene acetal were stable under the reaction conditions.

AB - A useful method for the selective cleavage of primary MPM ethers by using TMSI/Et3N is described. Other protective groups such as secondary MPM ethers, silyl ethers, and benzylidene acetal were stable under the reaction conditions.

KW - Deprotection

KW - MPM ether

KW - Selective cleavage

KW - TMSI

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DO - 10.1016/j.tetlet.2009.05.084

M3 - Article

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VL - 50

SP - 4552

EP - 4553

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 31

ER -