Serum anti-p53 antibody as a tumour marker for colorectal cancer screening

Masaya Iwamuro; Yoshinari Kawai; Tomoko Matsumoto; Masashi Uda; Hiroyuki Okada

doi:10.3332/ecancer.2015.560

Serum anti-p53 antibody as a tumour marker for colorectal cancer screening

Masaya Iwamuro, Yoshinari Kawai, Tomoko Matsumoto, Masashi Uda, Hiroyuki Okada

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A 60-year-old Japanese man presented to our hospital for further investigation of an elevated serum anti-p53 antibody level. He was diagnosed with colon cancer and the tumour was surgically resected. Histological diagnosis of advanced colon cancer without lymph node involvement or distant metastasis was made. It was noteworthy that both serum carcinoembryonic antigen (CEA) and a fecal occult blood test that were performed preoperatively were non-diagnostic. This case highlights the potential usefulness of serum anti-p53 antibody tests for detection of colorectal cancers. Moreover, sequential changes in the anti-p53 antibody levels after curative resection were observed.

Original language	English
Article number	560
Journal	ecancermedicalscience
Volume	9
DOIs	https://doi.org/10.3332/ecancer.2015.560
Publication status	Published - Jul 29 2015

Keywords

Anti-p53 antibody
Cancer screening tests
Colon cancers
Colorectal carcinoma
Early diagnosis of cancer

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3332/ecancer.2015.560

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abstract = "A 60-year-old Japanese man presented to our hospital for further investigation of an elevated serum anti-p53 antibody level. He was diagnosed with colon cancer and the tumour was surgically resected. Histological diagnosis of advanced colon cancer without lymph node involvement or distant metastasis was made. It was noteworthy that both serum carcinoembryonic antigen (CEA) and a fecal occult blood test that were performed preoperatively were non-diagnostic. This case highlights the potential usefulness of serum anti-p53 antibody tests for detection of colorectal cancers. Moreover, sequential changes in the anti-p53 antibody levels after curative resection were observed.",

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AU - Iwamuro, Masaya

AU - Kawai, Yoshinari

AU - Matsumoto, Tomoko

AU - Uda, Masashi

AU - Okada, Hiroyuki

N1 - Publisher Copyright: © the authors; licensee ecancermedicalscience.

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Y1 - 2015/7/29

N2 - A 60-year-old Japanese man presented to our hospital for further investigation of an elevated serum anti-p53 antibody level. He was diagnosed with colon cancer and the tumour was surgically resected. Histological diagnosis of advanced colon cancer without lymph node involvement or distant metastasis was made. It was noteworthy that both serum carcinoembryonic antigen (CEA) and a fecal occult blood test that were performed preoperatively were non-diagnostic. This case highlights the potential usefulness of serum anti-p53 antibody tests for detection of colorectal cancers. Moreover, sequential changes in the anti-p53 antibody levels after curative resection were observed.

AB - A 60-year-old Japanese man presented to our hospital for further investigation of an elevated serum anti-p53 antibody level. He was diagnosed with colon cancer and the tumour was surgically resected. Histological diagnosis of advanced colon cancer without lymph node involvement or distant metastasis was made. It was noteworthy that both serum carcinoembryonic antigen (CEA) and a fecal occult blood test that were performed preoperatively were non-diagnostic. This case highlights the potential usefulness of serum anti-p53 antibody tests for detection of colorectal cancers. Moreover, sequential changes in the anti-p53 antibody levels after curative resection were observed.

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KW - Early diagnosis of cancer

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Serum anti-p53 antibody as a tumour marker for colorectal cancer screening

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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